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Elsevier

Academic Press

  • Maternal-Fetal and Neonatal Endocrinology

    Physiology, Pathophysiology, and Clinical Management
    • 2nd Edition
    • Christopher S. Kovács + 1 more
    • English
    Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This new edition expands coverage of specific disorders and diseases beyond the current endocrinology content on the market making it the go-to reference for translational and clinical research scientists to appreciate the research gaps that require further investigation. It’s comprehensive coverage of pathophysiology, diagnosis, and treatments, will help readers better understand how various diseases present differently in pregnancy and lactation and how to respond to related complications.

  • Isothermal Titration Calorimetry in Enzymology

    Techniques and Applications
    • 1st Edition
    • Anthony Mittermaier + 1 more
    • English
    Isothermal Titration Calorimetry in Enzymology: Techniques and Applications provides a thorough, practical overview of ITC as a productive and powerful tool for quantifying enzyme catalysis and interactions with substrates, products, cofactors, and inhibitors. Here, global experts in the methodology discuss the full capabilities of ITC and how it may be applied in research, medicine, and industry and offer a basis to continue leveraging ITC as its uses expand and evolve. This book bridges the gap between research and application by giving extensive technical details on cutting edge ITC techniques across a wide swath of both ITC kinetics measurements and ITC thermodynamic measurements, alongside case studies illustrating the depth of knowledge that can be obtained. Applications discussed include measuring binding kinetics by ITC, analyzing ITC kinetic data, in vivo enzyme kinetics by ITC, analyzing enzyme kinetics in crowded solutions, studying catalysis of biological substrates, interpreting ITC binding curves, ITC in drug discovery, ITC in the development of cancer therapeutics, ITC analysis of aminoglycoside resistance enzymes, studying enzyme interactions with toxic metals, using ITC to study ubiquitination, and ITC studies of glycoside hydrolases, among others.

  • Polyamines-Phytohormones-Nutrients Network

    Nexus in Plant Responses to Abiotic Stresses
    • 1st Edition
    • Asim Masood + 3 more
    • English
    Polyamine-Phytohormo... Network: Nexus in Plant Responses to Abiotic Stresses presents the latest global research on key tools for improving physiological and biochemical mechanisms that enhance plant health and productivity.Exposur... of plants to abiotic stresses is inevitable, often leading to impaired growth, metabolism, and productivity. However, plants are naturally equipped with endogenous chemicals including intracellular messengers and signalling molecules that counteract potential stress impacts, protect cellular functions, and promote healthy growth and production. Polyamines (PAs) are low-molecular-weight... nitrogen-containing compounds with aliphatic polycationic properties. Beyond their role in growth and development, PAs enhance plant tolerance to abiotic stresses. Given their connection with phytohormones and mineral nutrients, understanding their interactions—whether synergistic or antagonistic—could shed light on their potential to mitigate these stresses.Written by a team of expert contributors, this volume in the Plant Biology, Sustainability, and Climate Change series focuses on the interactions among PAs, phytohormones, and mineral nutrients that are crucial for regulating nutrient assimilation, carbon fixation, and secondary metabolic pathways.

  • Sleep and Cancer

    • 1st Edition
    • Maria Paola Mogavero + 3 more
    • English
    Sleep and Cancer compiles novel information on the interactions between sleep and cancer. The book highlights how prevention and treatment of sleep disturbances in clinical cancer practice helps prevent the onset of tumors and their comorbidities, both short- and long-term. It analyzes how sleep disorder treatment improves the response to antitumor therapy in the long term, presenting procedures regarding cognitive-behavioral therapy of sleep disorders that are often overlooked in the oncological field.In addition, the book suggests new therapeutic approaches in oncology that are based on the knowledge of sleep mechanisms, such as chronotherapy, use of melatonin as an adjuvant in chemo- and radiotherapy, and orexinergic drugs.

  • Biopharmaceutical Ecosystems

    A Comparative Study of U.S. and European Systems
    • 1st Edition
    • David R. Williams
    • English
    The ecosystem perspective on organizations and economic settings is relatively new. It expands on work that looks at bio-clusters, concentrating on the relationship between human and financial capital. The perspective takes an expansive view of biopharmaceuticals in relation to stakeholders and the social, political, and economic landscape, including other life science companies, academia, non-profits, government entities, and health systems. The biotechnology and pharmaceutical industries have been merging for some time, with biotechnology often portrayed as a disruptive innovation to the pharmaceutical industry. A fuller description of this activity put into the greater context of the ecosystem perspective is warranted.Biopharmac... Ecosystems: A Comparative Study of U.S. and European Systems puts forward a picture of biopharmaceutical ecosystems in the USA and Europe. It examines and expands current thinking on the development of the ecosystem perspective on biopharmaceuticals. The title considers multiple locations, with countries in the top 15 of biopharmaceutical exporters selected. It pays particular attention to shifts in the political and economic landscape, and how such changes affect ecosystems. The underlying aim of biopharmaceutical ecosystems is to further the development of new drugs, reduce time to market, and lower costs. In explaining ecosystems, the book applies a quadruple helix model - academia; consumer/society; government; and industry - to each region and country in light of this triple aim.

  • Sustainable Advances in Biopolymer-Based Packaging for Food Shelf-life Extension

    • 1st Edition
    • Mihir Kumar Purkait + 2 more
    • English
    Sustainable Advances in Biopolymer-Based Packaging for Food Shelf-life Extension offers readers sustainable solutions for enhancing food shelf-life. It covers topics such as bio-based packaging materials, modification techniques, edible coatings, biodegradable packaging, nanotechnology, hydrogels, and intelligent packaging. Readers will be able to make informed decisions and implement sustainable solutions for enhancing food shelf-life while reducing reliance on traditional non-biodegradable packaging materials. The book begins by exploring the basics of bio-based food packaging materials, covering origins, characteristics, and varieties such as plant, animal, microbial, and waste materials.Subsequent chapters explain emerging bio-based materials, including intelligent packaging and edible coatings. Extraction technologies, modification techniques, and applications for sustainable and eco-friendly food packaging are also discussed. The potential of biopolymers, including those from plant extracts, to improve the nutritional content of packaged foods is highlighted. Through country-specific case studies from the EU, Asia, and North America, the book discusses the global regulatory landscape for bio-based food packaging and offers insights into challenges and future trends.

  • Functional Connectivity of the Human Brain

    From Mechanisms to Clinical Applications
    • 1st Edition
    • Maria A. Rocca + 1 more
    • English
    Functional Connectivity of the Human Brain: From Mechanisms to Clinical Applications is a comprehensive review of mechanisms and analysis of methods of functional connectivity to map brain organization in healthy individuals and sick patients. Providing full coverage of the discipline for a wide audience of different research and clinical specialists, this volume begins with descriptions of mechanisms of functional connectivity and methodological approaches to quantify it, followed by a focus on how functional connectivity has been used to describe brain function in healthy people and to characterize network disruption in diseased conditions. This practical balance in book structure is suitable for readers with a technical or clinical orientation, providing background that is easy to approach for clinicians or scientists. Chapters examine fMRI and electrophysiological techniques, brain maturation, aging, and cognitive neurosciences, as well as functional connectivity in neuroinflammatory, neurodegenerative, and neuropsychiatric conditions. Future perspectives look forward to functional connectivity in multimodal analysis, artificial intelligence, and more. This book will be of use to a wide audience working on functional connectivity experiments, as well as any courses on the topic.

  • Fundamentals of Brain Organoids for Neurological Diseases

    • 1st Edition
    • Balachandar Vellingiri + 1 more
    • English
    Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. Fundamental of Brain Organoids for Neurological Diseases provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms.

  • Clinical and Organizational Applications of Applied Behavior Analysis

    • 2nd Edition
    • Henry S. Roane + 3 more
    • English
    Clinical and Organizational Applications of Applied Behavior Analysis, Second Edition offers a comprehensive revision that delves into data-based decision-making to guide treatment selections for behavior changes across various populations and contexts. This edition's chapters thoroughly address vital aspects such as data collection, single-case research design methodology, objective decision-making, and visual data inspection. The book's updated content ensures that practitioners are well-equipped to implement effective and evidence-based procedures in diverse settings, from schools and homes to community environments. In addition to these foundational topics, the revised edition introduces new chapters that explore integrated healthcare, adjudication of children's academic interventions, and applied animal behavior.The book highlights the applied behavior analysts' role in utilizing research to develop and execute effective procedures, especially for addressing behaviors linked with autism and other developmental disorders. The principles of this therapeutic approach have shown increasing effectiveness when applied to a broader range of populations, settings, and behaviors.

  • Entomopathogenic Fungi in Insects

    From Physiological Effects to Applications
    • 1st Edition
    • Arash Zibaee + 2 more
    • English
    Entomopathogenic Fungi in Insects: From Physiological Effects to Applications explores the complex relationships between entomopathogenic fungi and insects. This interdisciplinary book delves into the physiological, immunological, and behavioral responses elicited by fungi in insects, offering insights for sustainable development. It assesses the potential applications of these fungi as biopesticides against harmful insects while considering their impact on non-target populations. This comprehensive work is invaluable for researchers and professionals in agroecosystems, insect pathology, biocontrol, plant protection, and crop health, as well as graduate students focused on sustainability.In addition, the book examines the mutualistic roles fungi can play in insect physiology, such as aiding in digestion. These fungi, prevalent in insect habitats, can serve as microbial pest control agents by infecting and weakening insect hosts. The book emphasizes the importance of mitigating potential harm to non-target insect populations, ensuring a balanced approach to biocontrol in agricultural practices.

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