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Academic Press

  • Baicalin

    Pharmacology, Clinical Applications, and Future Prospects
    • 1st Edition
    • Xiao Ma + 2 more
    • English
    Baicalin: Pharmacology, Clinical Applications, and Future Prospects consolidates foundational knowledge and recent advancements in baicalin research, addressing critical aspects such as efficacy, toxicity, and pharmacokinetics. The book is organized into three main parts, beginning with the Foundations of Baicalin Research, which explores the historical and traditional uses of Baicalin, extraction methods, and modern research advancements. The second part, Pharmacology of Baicalin, provides an in-depth analysis of its mechanisms of action, bioavailability, and pharmacokinetic parameters, while also presenting current applications in various diseases, including pulmonary, liver, cardiovascular, and nervous system disorders. Finally, the Prospects section addresses future directions in drug delivery and administration.By balancing scientific rigor with accessibility, this book is tailored for PhD students, postdoctoral researchers, and pharmaceutical professionals. It highlights cutting-edge research and practical applications, empowering readers to explore the full potential of baicalin in drug development and clinical practice.

  • Fostering Research Integrity

    A Practical Guide for Research Ethics
    • 1st Edition
    • Ashima Anand
    • English
    Fostering Research Integrity: A Practical Guide to Research Ethics, a new release in Elsevier's new series, Hot Topics in Physiology, addresses the aspects of research integrity, international normative instruments governing research integrity, and research practices. Additionally, the book covers emerging issues in ethics such as organoid research, AI, animals research, as well as data sharing and protection. Users will find this resource invaluable to any laboratory who utilizes animals in research—biology, physiology, cell biology, etc. It will also be vital to researchers involved in human research studies—universities and pharmaceuticals and would be vital for anyone doing research in any discipline.

  • Innovations and Human Factors Challenges in Healthcare Product Design

    • 1st Edition
    • Kamalpreet Sandhu + 3 more
    • English
    Innovations and Human Factors Challenges in Healthcare Product Design covers best practices and advanced design methods to capture, document, and validate various challenges at the early stage of the design process, also delving into how to mitigate design strategies to address those challenges without compromising the cost, effort, safety, and quality of the device. The book provides a comprehensive collection of technical notes, research designs, design methods and processes, case studies, comprehensive literature on the industrial impact of design methods and processes, and applications of digital technologies for design, analysis, manufacturing, testing, and deployment. Readers will find multidisciplinary coverage of the application of technology and science for product design in healthcare sectors.

  • Knowledge Graphs and Large Language Models

    Current Approaches, Challenges, and Future Directions
    • 1st Edition
    • Sanju Tiwari + 3 more
    • English
    Knowledge Graphs and Large Language Models: Current Approaches, Challenges, and Future Directions explores the cutting-edge fusion of two powerful artificial intelligence technologies: Large Language Models (LLMs) and Knowledge Graphs (KGs). The book is structured to provide a comprehensive understanding of this emerging field. Chapters introduce the synergy between LLMs and KGs, delve into the capabilities and challenges of LLMs, focus on the structure, function, and significance of KGs, present a conceptual framework for bridging LLMs and KGs, discuss techniques for their integration, explore how LLMs can enhance KGs and vice versa, and showcase applications of LLM-KG synergy across various domains.Final sections addresses ethical, social, and technical challenges and future innovations. The book concludes by summarizing key insights and advancements in intelligent systems. This is an essential resource for graduate students, researchers, and professionals in computer science. It offers valuable insights for adopting LLMs, KGs, and their advanced applications in research and product development. By bridging the gap between these technologies, this book equips readers with the knowledge to drive innovation and enhance the capabilities of intelligent systems.

  • Bio-functional Cosmetics for Health

    Exploring Nature’s Ingredients for Safety, Efficacy, and Sustainability
    • 1st Edition
    • Alexandros Tsoupras + 1 more
    • English
    Bio-functional Cosmetics for Health: Exploring Nature’s Ingredients for Safety, Efficacy, and Sustainability bridges the gap between cosmetics, nutraceuticals, and pharmaceuticals, providing the latest research for developing health-promoting cosmeceuticals and nutricosmetics from various food sources and food waste. From medicinal plants, teas, cacao, coffee, fruits, vegetables, plant oils, nuts, and cereals to marine microorganisms, fungi, insects, crustaceans, and more, this book takes a close look into the safety, efficacy and sourcing of bioactives from these food sources and how they can be sustainably used as ingredients to create bio-functional cosmetics, cosmeceuticals and nutricosmetics.Reade... will gain insight on the anti-inflammatory, antioxidant, anti-aging, and anti-cancer properties of bioactive ingredients in cosmetics and will also be informed on the latest regulatory and safety issues and R&D trends for the application of bioactives in functional cosmetics and cosmeceutical products.

  • Alternatives to Antibiotics for Sustainable Aquaculture

    • 1st Edition
    • Baskaralingam Vaseeharan + 2 more
    • English
    Alternatives to Antibiotics in Sustainable Aquaculture explores issues associated with antimicrobial use and available alternatives to support aquatic animal health. The book unveils the issues related to antimicrobial use and offers alternative approaches to foster a more sustainable global aquaculture industry. These approaches encompass natural-based antibiotic substitutes, antimicrobial peptides, probiotics, prebiotics, and postbiotics, as well as immunostimulants and feed additives. Additionally, chemical alternatives, vaccines, bacteriophages, quorum quenching, and antibiofilm approaches are explored. The future of aquatic animal health is covered through the lens of novel technologies, including genomic and metabolomic approaches, nanotechnology, and nanobubble methods.This book provides insightful knowledge for individuals from both academic and private sectors, as well as policymakers and regulators. The knowledge gathered in this book is intended to positively guide aquaculture supply chains toward a sustainable transformation of the industry.

  • Precision Technologies for Digital Agriculture

    Harnessing IoT, Big Data, Crop Modeling, and AI for Agricultural Production
    • 1st Edition
    • Sushil Kumar Himanshu + 2 more
    • English
    Precision Technologies for Digital Agriculture: Harnessing IoT, Big Data, Crop Modeling, and AI for Agricultural Production investigates the growing role of computational and connected approaches in contemporary agricultural environments, bringing together recent findings in artificial intelligence, sensing infrastructures, agroecosystem modeling, and data analytics to illustrate decisive shifts toward more accurate, forward-looking, and responsive decision-making.Earl... chapters set out the theoretical and technical underpinnings of digital and precision agriculture, addressing automation, data stewardship, privacy, and the development of dependable AI‑based tools. These foundations support a detailed overview of key technological building blocks, including remote and proximal sensing, geospatial platforms, machine vision, digital twins, and the Internet of Living Things, with emphasis on their contribution to integrated system management and optimized resource allocation.Later sections concentrate on applied methods across field operations. Topics include climate‑adaptive, smart irrigation, soil and microbial diagnostics, UAV‑enabled monitoring, and algorithmic frameworks to yield estimation and nutrient regulation. Across these chapters, attention is given to both implementation constraints and enabling factors, including interoperability, data security, and scalability.The volume concludes with regionally grounded case studies and economic assessments that explore adoption strategies, governance arrangements, and cost–benefit considerations across diverse crops and production settings. Together, these cutting-edge analyses provide a structured assessment of how digital technologies are being translated into transformative agricultural practice, and of the contextual conditions under which their effective use can be fully realized.

  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1st Edition
    • Ashutosh Pareek + 4 more
    • English
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.

  • Investigative and Predictive Forensic Microbiology

    • 1st Edition
    • Hirak Ranjan Dash
    • English
    Investigative and Predictive Forensic Microbiology showcases the latest advancements in microbial technology for forensic applications, covering a wide range of topics in forensic microbiology. Sections explore human normal microflora, cover classical methods of analyzing microbes, discuss microbial tools in forensic medicine that address post-mortem analysis, and delve into microbial biomarkers for estimating time of death. Investigative microbiology topics include analyzing body fluids, geolocation prediction using microbes, ancient microbial DNA analysis, biodefense, and emerging infections.The book's final section focuses on challenges and future approaches, covering statistical interpretation of data, regulatory considerations, and ethical implications of forensic microbiology. With contributions from renowned experts in the field, this book is a comprehensive resource for researchers and practitioners in microbiology, genetics, forensic science, and for law enforcement professionals and advanced students.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

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