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Academic Press

  • Conceptual Breakthroughs in Comparative Animal Physiology

    • 1st Edition
    • James Hicks + 1 more
    • English
    Conceptual Breakthroughs in Comparative Animal Physiology tells a story of innate human curiosity about the natural world, and a deeply creative discipline, shaped by varied environments, unusual organisms, elegant experiments, and the persistent effort to understand how animals work and why they work the way they do; and along the way discovery of “adaptations and mechanisms of the most surprising character”.Written by two leading experts in the field, each chapter reflects on the origins of ideas and the approach of turning natural diversity into experimental design. From deserts to oceans, from the anoxia-tolerant animals to endothermic insects, from deep-diving mammals to the integration of ‘omics’; each chapter follows the discoveries and people who were compelled to modify their view of "what life can do". The chapters also highlight the long-term influence of key conceptual breakthroughs, demonstrating how insights from comparative physiology have shaped not only the field itself but also, ecology, evolution, and engineering. As scientists strive to understand the complexity of, the book underscores the inherit integrative nature of, revealing a process that strives to connects genes to organisms and organisms to environments, and providing a framework understanding the diversity of life. This is an essential resource for undergraduates, graduate students and researchers interested in physiology with its comprehensive synopsis on the field’s foundational history and significant advances.

  • The AI Frontier in Molecular Modelling and Drug Designing

    • 1st Edition
    • Manish Kumar Gupta + 2 more
    • English
    The AI Frontier in Molecular Modelling and Drug Designing aims to provide a comprehensive guide on the application of AI concepts in drug designing, discovery, and molecular modeling. The book delves into machine and deep learning techniques that predict structural properties of molecules, identify druggable pockets, and assess physicochemical properties of targets. Sections explore current and potential computational resources to tackle complex biological challenges. Each chapter is enriched with relevant examples, text boxes, and case studies that illustrate the practical application of AI techniques, their outcomes, and the challenges faced during implementation.This resource is tailored for researchers, students, and professionals in both academia and industry, providing them with the latest methodologies, advancements in technology, and practical insights into AI-driven drug research, structural biology, computational biology, and translational science.

  • Insomnia Disorder

    The Treatment Program SLEEPexpert for Clinical Practice
    • 1st Edition
    • Christoph Nissen + 2 more
    • English
    Treating Insomnia: The Treatment Program SLEEPexpert for Clinical Practice is a comprehensive guide designed to transform insomnia treatment in clinical settings. Beginning with a review of the essential connection between sleep and health, the book presents the intricate regulation of sleep and the critical diagnostic criteria for insomnia. This book highlights the importance of cognitive behavioral therapy for insomnia (CBT-I) as the frontline intervention while addressing the alarming trend of inadequate implementation and reliance on pharmacological treatments that often lead to unwanted side effects.The development of SLEEPexpert—a tailored adaptation of CBT-I—is introduced as a pivotal solution, offering a structured treatment manual that outlines its foundational principles and the three distinct phases of the program. With practical tips and specific goals for implementation, this book equips healthcare professionals with the necessary tools to effectively integrate SLEEPexpert into their practices.

  • Cellular Therapies for Cancer Treatment

    Advancements in Drug Delivery Strategies
    • 1st Edition
    • Arun Kumar Singh + 3 more
    • English
    Cellular Therapies for Cancer Treatment: Advancements in Drug Delivery Strategies explores the innovative use of cellular therapy to combat cancer, placing an emphasis on state-of-the-art delivery approaches. By covering a variety of cellular therapies for cancer, such as stem cells, immune cells, and others, this book provides a comprehensive introduction to the field. It describes ways to deliver drugs that target cancer cells more efficiently, decrease off-target effects, and enhance therapy outcomes. Sections provide a brief overview of cancer cell biology, describe the need for advance drug delivery systems, and address challenges and future directions.The book also goes into the ideas behind cellular therapies and how they may overcome drug resistance and make existing cancer treatments more effective. By elaborating on the value of diversity and inclusion in cancer research and treatment, the book also emphasizes the importance of all patients having equal access to innovative therapies. All things considered, this book is a great tool for researchers, doctors, and students in the cancer treatment sector.

  • Biopolymer Based Nano Drug Delivery for Cancer Wound Healing

    • 1st Edition
    • Vipan Kumar + 5 more
    • English
    Biopolymer Based Nano Drug Delivery for Cancer Wound Healing explores groundbreaking advancements in nanomedicine's role in treating cancer and promoting wound healing. The book delves into the pathophysiology of cancerous wounds, introduces biopolymer-based nanomedicine, and examines drug delivery systems using biopolymer-based nanoparticles. It concludes with future prospects of biopolymers in antitumor drug delivery systems. This resource is invaluable for researchers, advanced students, and R&D personnel across various fields, including cancer research, polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry. Each chapter bridges theoretical concepts with practical applications, providing examples to illustrate key points.The book covers the pathophysiology of cancer and wounds, biopolymer-based nanomedicine for cancerous wounds, and drug delivery systems for healing. This is an essential reference for scientists and students focusing on pharmacy, drug delivery, and biomedicine.

  • RNases in Health and Diseases

    From Housekeeping Enzymes to Moonlight Proteins
    • 1st Edition
    • Ester Boix
    • English
    RNases in Health and Diseases: From Housekeeping Enzymes to Moonlight Proteins provides coverage of the structural and functional properties of RNases, introducing new concepts such as their recently discovered multifaceted properties, their involvement in the generation of non-coding signaling RNAs, and their proposed uses as diagnostic and therapeutic tools. This book's sections cover the structure of RNases, present research methods and tools to study RNases, and delve into RNases and diseases. Users will find a wider perspective on the topics discussed that will serve researchers and students engaged in the study of RNases who are interested in acquiring a better understanding.

  • Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture

    • 1st Edition
    • Douglas P. Beall
    • English
    Worldwide, vertebral compression fractures (VCFs) continue to be the most common major fragility fracture, affecting patients over the age of 50, and osteoporosis is the most prevalent condition associated with VCFs. Patient Treatment and Management Following an Osteoporotic Vertebral Compression Fracture provides treatment and management guidance of the osteoporosis disease process in patients who have had a VCF. This book opens with a foundation of osteoporosis and VCF and then reviews clinical and radiological assessment approaches, evaluation, treatment, and ongoing management options. Subsequent chapters cover the efficacy of the different vertebral augmentation types on patient outcomes, optimization methods, decisions for osteoporosis treatment in these patients, and recommendations to improve patient outcomes. Special attention is paid to the treatment sequence and objectives following an osteoporotic VCF. This book concludes with coverage of insightful developments in clinical management and current research and features targeted case studies representing common patient characteristics that showcase varying aspects of different VCFs and the underlying osteoporosis that gives rise to these fractures. This title serves as an invaluable resource for any practitioner managing fragility fractures in older patients as well as treating their underlying osteoporosis.

  • Neuroscience of Social Behavior

    Bridging the Mind and Society
    • 1st Edition
    • Mikhail Votinov
    • English
    Neuroscience of Social Behavior: Bridging the Mind and Society aims to explore social behavior, connection, and communication through the lens of neuroscience. This book offers a comprehensive exploration of the latest research and practical applications in the field, making complex brain science accessible. By providing practical insights and real-world examples, this book empowers readers to apply their newfound knowledge to better understand mechanisms of social skills, empathy, mentalizing and social decision-making.

  • Nano Drug Delivery Systems for Colon Cancer

    Innovations, Challenges, and Applications
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nano Drug Delivery for Colon Cancer: Innovations, Challenges, and Applications is a breakthrough exploration that delves into the latest advancements in colon cancer diagnosis and treatment. This comprehensive guide, composed of 11 detailed chapters, focuses on the design, synthesis, and application of various nanodrug delivery systems, showcasing how nanoparticulate drug carriers can significantly enhance therapeutic efficacy through strategic design. Aimed at graduates, clinical researchers, and scientists, this book addresses the complexities and challenges in drug and gene delivery. Beyond its technical insights, the book highlights the global health impact of colon cancer and offers a roadmap for developing more efficient and targeted treatments.It serves as a vital resource, fostering interdisciplinary knowledge and advancements that have the potential to revolutionize colon cancer therapeutics. The book's interdisciplinary approach ensures it is a beacon of knowledge for those seeking to navigate and innovate within this critical field.

  • PEGylated Nanocarriers: Applications in Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    PEGylated Nanocarriers: Applications in Drug Delivery explores the essential properties of PEG that contribute to the creation of long circulating nanocarriers and examines the significant biological and pharmacological impacts of PEGylation and extended circulation. This book provides a detailed review of the preparation, properties, and applications of various long-circulating PEGylated nanocarriers, such as liposomes, nanoparticles, dendrimers, carbon nanotubes, and more. Key chapters also include analysis of the challenges, biological toxicity, and safety issues associated with PEGylated nanocarriers, enabling better clinical translation. PEGylated Nanocarriers: Applications in Drug Delivery is of interest to researchers and academics in the fields of biomaterials, pharmaceutical science, and polymer science, with an interest in developing PEGylated drug delivery systems for therapeutics.

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