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Academic Press

  • Strategic and Technological Pathways for a Decarbonized Economy

    From Industry 4.0 to 5.0
    • 1st Edition
    • Fatima Zahra Benbrahim + 3 more
    • English
    Strategic and Technological Pathways for a Decarbonized Economy offers readers, including researchers, energy professionals, investors, policymakers and corporate leaders, credible, forward-looking information to support the transition to a low-carbon economy. For researchers, there is a wealth of data and frameworks to advance innovation. Provides energy stakeholders with expert insights into technology deployment and regulation. Risk-return profiles, market trends, and ESG metrics will be of particular interest to investors and innovators. For policymakers, the book includes modeling and impact assessments to guide climate policy. Presents corporate leaders with strategic roadmaps, emissions benchmarks and tools to align sustainability with business goals. By offering a framework for understanding the evolution of industrial practices, the book enables readers to prepare for future challenges while equipping them with the tools needed to succeed in a decarbonized economy.

  • Nanotechnology in Brain Tumor Treatment

    Unveiling Molecular Mechanisms and Pioneering Therapies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanobiotechnology in Brain Tumor Treatment: Unveiling Molecular Mechanisms and Pioneering Therapies is a groundbreaking resource that addresses the formidable challenges posed by brain tumors in oncology. This comprehensive book explores the etiology, symptoms, diagnosis, and treatment options for brain tumors, with a particular focus on the revolutionary impact of nanobiotechnology. By integrating cutting-edge research on nanotechnology with practical applications in neuro-oncology, this book offers a unique perspective on enhancing patient outcomes and advancing brain cancer treatment strategies.By offering a comprehensive overview of nanobiotechnology in brain tumor treatment, this resource serves as a vital tool for those involved in the research, diagnosis, and treatment of brain cancers, paving the way for innovative and personalized therapeutic approaches.

  • Apolipoprotein E in Health and Disease

    Unravelling its Intricate Roles
    • 1st Edition
    • Dileep Kumar + 2 more
    • English
    Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

  • Protein Misfolding and Human Diseases

    Deciphering the Central Role of Pathological Aggregation
    • 1st Edition
    • Pranav Kumar Prabhakar + 2 more
    • English
    Protein Misfolding and Human Diseases: Deciphering the Central Role of Pathological Aggregation investigates the misfolding of proteins and implications for a variety of debilitating conditions. The book comprehensively overviews pathological protein aggregation, exploring its mechanisms in specific illnesses, including Alzheimer's disease, Parkinson’s disease, Huntington’s disease, prion diseases, ALS, and systemic amyloidosis. It addresses disrupted cellular pathways and failures in protein homeostasis during aging, delineating the unifying principles across protein conformational disorders. Sections feature structural insights into protein aggregates from amyloid fibrils to inclusion bodies and offer therapeutic strategies to disrupt aggregation pathways, enhance cellular protein quality control, and provide immunotherapy solutions.Finally, the book closes with a discussion of the latest advances in research and considerations for future directions to combat protein aggregation. It will serve as an invaluable reference on the intricacies of protein misfolding and its clinical implications. Researchers, academics and graduate students working across these fields will benefit from this comprehensive guide. Additionally, clinicians and healthcare professionals will find it invaluable for understanding the molecular basis of protein misfolding disorders.

  • An Authoritative Guide to Chronic Pediatric Abdominal Pain

    Pathophysiology, Diagnosis and Management
    • 1st Edition
    • Miguel Saps + 1 more
    • English
    An Authoritative Guide to Chronic Pediatric Abdominal Pain: Pathophysiology, Diagnosis and Management provides a comprehensive and extensive overview of all aspects relevant to the care of children with abdominal pain. It includes chapters tailored to each discipline, level of training, and primary interest (clinical or research), covering daily practice, diagnosis, testing, conventional and complementary treatments, interdisciplinary care, and the transition to adult gastroenterology treatment. The book critically updates the evidence behind these methods and prepares readers to understand more advanced techniques. Topics include early adverse life events, intestinal permeability, visceral hypersensitivity, sex differences, microbiome infections, use of antibiotics, and the microbiome.Informati... on clinical perspectives and management in the emergency department helps inform pediatricians, gastroenterologists, residents, fellows, and nurse practitioners about the scientific basis for prior workups, differential diagnoses, and the rationale behind them. In addition, this book helps clinicians understand the basic research behind these factors, how they influence pathophysiology, clinical presentation, progression, and outcomes.

  • Get to Know Your Employee

    Secrets of A Successful Company
    • 1st Edition
    • Janek Musek
    • English
    Get to Know Your Employee: Secrets of a Successful Company addresses the critical and often overlooked psychological factors that influence organizational performance and employee relations. Drawing on cutting-edge research in organizational psychology, neuroscience, and developmental science, this reference provides a comprehensive analysis of how early life experiences, repressed fears, and defensive behaviors can undermine workplace efficiency, creativity, and well-being. The book fills a crucial gap by revealing the hidden causes of organizational challenges that traditional management strategies often overlook. The reference is structured to guide readers through a logical progression, beginning with foundational concepts and the unknowns that must be recognized in organizational settings. Subsequent chapters examine the role of early experiences and brain development, the impact of parenting styles, and the mechanisms by which early stress translates into defensive behaviors. The text further explores motivational loops, approach-avoidance behaviors, and the neuroscientific underpinnings of workplace dynamics. Practical solutions are presented for managers and leaders, including methods for reassuring employees, building job satisfaction, and strengthening organizational culture. Appendices, references, and supportive figures enhance the utility of the content. Get to Know Your Employee equips organizational leaders, managers, psychologists, and allied professionals with a scientifically grounded framework for diagnosing and resolving persistent workplace problems. By addressing the psychological roots of organizational dysfunction, the reference empowers readers to foster healthier, more productive, and more innovative work environments. This work is essential for those seeking to align organizational values with behaviors, improve employee satisfaction, and achieve sustainable business success.

  • Biology of Aging Accelerators

    Fundamentals, Hallmarks and Therapeutic Interventions
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    Biology of Aging Accelerators: Fundamentals, Hallmarks and Therapeutic Interventions explores how biological, genetic, and environmental factors affect cellular and systemic homeostasis and lead to accelerated aging. The book begins with a historical perspectives, highlighting the growth in immune system deterioration, chronic illness, and social issues. It then examines the hallmarks of aging, including primary, antagonistic, and integrative characteristics that may or may not be contributors. Subsequent chapters explore basic concepts and key accelerators in human biology, the role of biological clocks, and mechanisms of aging accelerators such as cellular senescence, DNA damage, and mitochondrial dysfunction.The book also addresses how different organs age at different rates and the brain's role as the body's aging integrator and provides actionable insights into innovative therapies aimed at reducing or stopping the signs and symptoms of aging, including developments in medications, lifestyle adjustments, regenerative medicine, and cutting-edge technologies like stem cell therapy and CRISPR. By integrating scientific research and practical insights, this book offers a realistic perspective on anti-aging research and stimulates novel ideas for improving quality of life.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Green Intrusion Detection Systems for IoT

    • 1st Edition
    • Saeid Jamshidi + 3 more
    • English
    Green Intrusion Detection Systems for IoT tackles the pressing security challenges posed by the rapid expansion of the Internet of Things (IoT). The book delves into innovative, lightweight security models and energy-aware IDS mechanisms that strike a balance between security efficacy, computational efficiency, and environmental sustainability. Sections discuss the transformative role of IoT and the need for sustainable security solutions, highlight the distinctions between traditional and Green IDS, focus on lightweight security models essential for resource-constrained IoT devices, and delve into energy-efficient network designs.Additional sections explore green IDS mechanisms, including machine learning and distributed approaches, IoT vulnerabilities and mitigation strategies, practical examples of sustainable IDS in various smart environments, real-world case studies, and future directions in sustainable IoT security. The book concludes with actionable recommendations that align technological advancements with global sustainability goals.

  • Marine Mercury Bioaccumulation

    • 1st Edition
    • Luiz Drude de Lacerda
    • English
    Marine Mercury Bioaccumulation presents state-of-the-art research on mercury bioaccumulation in marine life. Written by leading experts in marine toxicology, this book delivers the latest information on monitoring and modeling mercury biomagnification in key marine taxa. Early chapters introduce the basic biology and ecology of how mercury travels through marine organisms and accumulates within marine food webs. Central chapters discuss the current status and exposure risks of key taxa, including marine vegetation, invertebrates, fishes, mammals, and birds. The book concludes with an assessment of human exposure to mercury through seafood products and novel modeling tools to assess environmental exposure risks and bioaccumulation.User... will find this to be a great resource for a global assessment of mercury contamination in the ocean, including biological resources, monitoring and modeling, current tools, existing research gaps, and suggestions on how to improve our monitoring and policy tools for improved safety of marine life and human consumption. This is an indispensable tool for researchers, resource managers, fisheries stakeholders, and students alike.

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