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Elsevier

Academic Press

  • The Future of Health and Economic Resiliency in Africa

    • 1st Edition
    • Muhammad Pate + 1 more
    • English
    Grown out of a Lancet Commission to look at the future of health and economic resiliency of Africa, The Future of Health and Economic Resiliency takes a multidisciplinary approach across numerous sectors of analysis, central to Africa’s future well-being. This book serves as a comprehensive analysis of the current state of the continent and what actions can be taken to improve health and resiliency moving forward. While previous analysis has been done regionally within the continent (sub-Saharan Africa, for example) or by specific health needs (HIV or poverty, for example), this book will be the first to synthesize a cross sector approach pan-Africa. By describing the context and through actionable solutions for the future, this book sets the framework for a more resilient Africa and global future. Future of Health and Economic Resiliency is a collaboration of top African experts and practitioners in public health, health systems, economics, financing, nutrition, climate, youth representation, and the private sector.

  • Geostatistical Approaches to Environmental and Public Health Issues

    • 1st Edition
    • Deepak Kumar + 4 more
    • English
    Geostatistical Approaches to Environmental and Public Health Issues is a timely and comprehensive examination of how geostatistical techniques can be leveraged to better understand and respond to pressing environmental and public health challenges. As the availability of large-scale spatial and temporal data continues to grow, so too does the demand for advanced tools that can navigate the complexity of real-world phenomena. This volume bridges methodological innovation with applied research, making it an essential resource for scientists, policymakers, and public health practitioners. Environmental and health-related events—such as air and water pollution, disease outbreaks, nutritional deficits, maternal and child health risks, and exposure to natural hazards like floods, droughts, and earthquakes—are inherently spatial and often uncertain. Traditional statistical models fall short in capturing the intricate patterns and dependencies involved. This book showcases how techniques like kriging, spatial regression, Bayesian modeling, and space-time analysis offer powerful, nuanced insights into these issues. Emphasizing stochastic, non-deterministic approaches, the volume highlights the importance of modeling uncertainty in both environmental and health domains. Through case studies and research-driven chapters, it demonstrates how integrating geospatial and statistical methods can enhance our understanding of where, why, and how events occur—ultimately improving the precision of health interventions and environmental policies. By aligning cutting-edge statistical approaches with the geospatial dimensions of health and environmental data, this book fills a critical gap in the literature and supports more targeted, data-driven decision-making in the face of global uncertainty.

  • Animal Models of Disease Part F

    • 1st Edition
    • Volume 211
    • English
    Animal Models of Disease, Part F, Volume 212 in the Methods in Cell Biology series, presents significant advancements in understanding disease mechanisms through animal models. The book features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

  • Advances in Biogerontology

    • 1st Edition
    • Volume 4
    • English
    Explore the latest breakthroughs in aging research with Advances in Biogerontology Volume 4. This comprehensive volume brings together cutting-edge studies on the biological mechanisms of aging, regenerative medicine, and interventions to promote healthy longevity. Featuring contributions from leading scientists worldwide, it delves into innovative approaches to slow, halt, or reverse age-related decline, offering insights into cellular aging, genetic factors, and emerging therapies. Ideal for researchers, clinicians, and students, this volume is a vital resource for understanding the future of aging and extending healthspan. Stay at the forefront of biogerontology with this authoritative collection of scientific advancements.

  • Decision Neuroscience

    • 2nd Edition
    • Jean-Claude Dreher
    • English
    Decision Neuroscience: An Integrative Perspective presents the most recent and compelling lesional, neuroimaging, electrophysiological... and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of the neural mechanisms behind reward and decision making. The neural bases of reward and decision-making processes are of critical interest to scientists because of the fundamental role that reward plays in a number of behavioral processes (such as motivation learning, and cognition), and because the neural bases have theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders. This book will constitute a comprehensive update of ground-breaking work addressing fundamental questions about the nature of behavior: how does the brain process reward and how does it make decisions when facing multiple options? And will feature entirely new content, as well as expanded coverage on drug and behavioral addiction, the role of subthalamus stimulation in neurological disorders and neuroeconomics.

  • Digital Twins and RF imaging for Wireless Networks

    • 1st Edition
    • George C. Alexandropoulos + 1 more
    • English
    Digital Twins and RF imaging for Wireless Networks presents the concept of digital twins, covering topics such as efficient estimation of high-dimensional channel matrices, real-time predictive maintenance, distributed learning for smart city applications, energy-efficient sensing and communications for the Internet of Things (IoT), autonomous vehicles, and adaptive channel coding for network task offloading. The second part focuses on radio-frequency imaging, discussing innovative approaches such as neural network designs for electric field integral equations, dynamically reconfigurable metasurface antennas, reconfigurable intelligent surfaces, extremely large antenna arrays in the near-field region, wideband multi-antenna radar, multimodal sensing and point cloud processing, and much more.Each chapter offers cutting-edge insights and methodologies that are expected to drive the future of wireless communication and sensing technologies. The rising demands of novel wireless communication applications, dynamic operating environments, and intricate traffic and user patterns are accelerating the transformation of wireless networks into distributed platforms that integrate communications, sensing, and computing to enable immersive functionalities. Digital twins and radio-frequency imaging are two rapidly evolving technologies poised to revolutionize sixth-generation (6G) and beyond wireless networks.

  • Molecular Pathology

    The Molecular Basis of Human Disease
    • 3rd Edition
    • Gregory J. Tsongalis + 1 more
    • English
    Molecular Pathology: The Molecular Basis of Human Disease, Third Edition is a comprehensive reference that explores the molecular mechanisms and basis of major human diseases. Expertly crafted, this book is designed for use as a teaching tool for medical students, biomedical graduate students, and allied health students. It serves as an advanced resource for pathology residents, postdoctoral fellows, basic scientists, and physician scientists engaged in disease-related research, presenting traditional pathology in the context of translational molecular medicine. In this new edition, the chapters have been fully updated and rearranged for better logical flow.Notably, four new chapters have been included, covering topics such as the pathogenesis of fibrotic diseases, mechanisms of mutation, molecular basis of soft tissue disease and pathology, and pathogenesis and pathophysiology. The book remains an invaluable reference for anyone seeking a deeper understanding of the molecular aspects of human disease.

  • Structural Biology of Amyloid Fibrils

    • 1st Edition
    • Vijay Kumar + 1 more
    • English
    Structural Biology of Amyloid Fibrils provides a comprehensive reference on the structure of protein aggregates in different neurodegenerative diseases, along with their molecular bases. Chapters describe these structures in detail, highlighting their similarities and differences across different disease states along with an unprecedented overview of current developments and new hypotheses emerging in amyloid fibril structure, stability and mechanisms of formation. The book also discusses how amyloid structure may affect the ability of fibrils to spread to different sites in a prion-like manner, as well as their role in disease. Featuring chapters on NMR, X-ray crystallography, and Cryo-EM methods, and discussing the structure of amyloid fibrils obtained directly from patients, the book allows readers to understand how polymorphism is associated with disease phenotype and how fibril structure affects and influences the cellular environment. Understanding the molecular architecture of amyloid fibrils and oligomers will be an important step towards developing therapeutic interventions based on targeting the fibrils and oligomers themselves and the processes that generate them.

  • Structural and Functional Dynamics of Nontuberculous Mycobacterium Proteins

    Insights into Pathogenic Mechanisms
    • 1st Edition
    • Parissa Farnia + 3 more
    • English
    Structural and Functional Dynamics of Nontuberculous Mycobacterium Proteins: Insights into Pathogenic Mechanisms explores the structural and functional dynamics of nontuberculous mycobacterium (NTM) proteins, focusing on their roles in pathogenicity, the mechanisms underlying microbial infections, and the potential for developing targeted therapeutic strategies to combat these emerging pathogens. The book begins with a foundational overview of nontuberculous mycobacteria (NTM), distinguishing them from Mycobacterium tuberculosis, their epidemiology, clinical significance, and structural biology. It discusses key structural features of NTM proteins and advanced techniques for protein structure determination, proteomic analyses, and bioinformatics approaches.Additiona... sections investigate the pathogenic mechanisms and the complexities of the host-pathogen interaction. Concluding with insights into emerging research, interdisciplinary collaboration, future treatment, and prevention strategies, this book is a helpful resource for researchers and healthcare professionals engaged in the study of infectious diseases.

  • Obesity

    Integrating Physiological, Pathophysiological and Clinical Perspectives
    • 1st Edition
    • Javier Gonzalez
    • English
    Obesity: Integrating Physiological, Pathophysiological and Clinical Perspectives, a volume in Elsevier's Hot Topics in Physiology series, provides coverage across a wide range of physiological disciplines, covering obesity science at a sufficient level to be understood by physiologists who may not be an expert in all subdisciplines, and with an aim of unifying physiological perspectives on obesity. Divided into three sections, the book covers causes of obesity (e.g., regulation of energy balance), the consequences of obesity (e.g., metabolic, disease risk etc.), and strategies to prevent and/or manage obesity (e.g., bariatric surgery, pharmacotherapy, and lifestyle).This volume is published in association with the International Union of Physiological Sciences (IUPS). It will be of great interest for clinicians, dieticians, exercise physiologists, and molecular biologists.

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