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Elsevier

Academic Press

  • Nanocomposite Biosensors for Healthcare Applications

    • 1st Edition
    • Prashant Kesharwani
    • English
    Nanocomposite Biosensors for Healthcare Applications examines the critical role of nanocomposites in advancing biosensor technology for clinical and biomedical applications. The book provides a single reference point, covering the design, fabrication, unique properties, and diverse healthcare applications of nanocomposite biosensors. A detailed review of a range of nanocomposites is offered, including graphene, gold nanoparticles, carbon nanotubes, and quantum dots. In addition, various biosensors and their benefits are assessed, such as wearable biosensors, lab-on-a-chip systems, and point-of-care devices, with key healthcare applications in managing diabetes, cancer, cardiovascular diseases, and infectious diseases thoroughly explored.This book also addresses regulatory, sustainability, and commercialization challenges, providing a detailed overview of how nanocomposites are reshaping diagnostics and healthcare. It is a valuable reference for researchers and academics in materials science, biomedical engineering, and pharmaceutical science, and may also appeal to healthcare professionals interested in nanocomposites and innovative biosensors for various clinical applications.

  • Biosimilars in Cancer

    • 1st Edition
    • Ranjita Shegokar + 1 more
    • English
    Biosimilars in Cancer is a comprehensive resource addressing the role of biosimilars in treating various cancer types. This book offers a succinct yet thorough overview of current trends in oncology, covering 21 different cancers from liver to breast cancer. Each chapter provides detailed insights into the latest trends, fundamental facts, and practical and clinical data, making it an invaluable tool for academics and practitioners. By compiling this rich content into a single, accessible volume, the book empowers researchers and clinicians to enhance their understanding, and improve patient outcomes through the effective use of biosimilars in oncology. Targeted primarily at pharmaceutical researchers, biomedical scientists, and clinicians, Biosimilars in Cancer supports the growing oncology biosimilars market. It also provides critical insights for those involved in cancer diagnostics and clinical trials, helping them stay ahead in this rapidly progressing field.

  • Gold Nanoparticle Therapeutics in Alzheimer's Disease

    Revolutionizing Diagnosis and Treatment
    • 1st Edition
    • Arun Kumar Singh + 2 more
    • English
    Gold Nanoparticle Therapeutics in Alzheimer's Disease: Revolutionizing Diagnosis and Treatment is an essential resource that delves into the groundbreaking use of nanotechnology in the fight against one of the most challenging neurodegenerative disorders. This volume offers an in-depth exploration on how gold nanoparticles can be used to enhance the diagnosis, treatment, and overall understanding of Alzheimer's disease. By examining the molecular mechanisms that enable nanoparticles to cross the blood-brain barrier, the book highlights their role in inhibiting amyloid fibrils and their potential as precise diagnostic tools.Covering a wide range of topics, this comprehensive guide serves as an invaluable reference for researchers, clinicians, and industry professionals at the forefront of Alzheimer's research and nanomedicine.

  • Necroptosis

    A Programmed Cell Death Machinery in Human Health
    • 1st Edition
    • Pratyusha Mandal
    • English
    Necroptosis: A Programmed Cell Death Machinery in Human Health provides a comprehensive review of the evolving concepts of programmed cell death (PCD) machinery. The book traces the evolutionary origin of necroptosis, necroptotic proteins, and how the proteins contribute to necroptosis and other cell death pathways. It clarifies necroptosis as more than merely an alternate to extrinsic apoptosis but explores it as an inflammatory form of cell death interconnected with multiple death signaling that ultimately dictates physiological outcome. Coverage summarizes the role of the death pathway and proteins in mammalian health and disease as well as key diseases where they play recognized contributing roles. The involvement of necroptosis in pulmonary diseases including activation during SARS-CoV2 infection is covered along with other gastroenteric diseases, cancer, and aging. Beyond conveying clinical knowledge, these topics will be of strong research interest to the biomedical bench scientist.

  • Predictive Digital Twins

    Foundations and Applications
    • 1st Edition
    • Agus Hasan
    • English
    Predictive Digital Twins: Foundations and Applications addresses the theoretical foundations, practical applications, and emerging trends associated with predictive digital twins. Specifically focusing on predictive capabilities, digital twins designated for this purpose are commonly known as predictive digital twins. Despite the growing recognition of their importance, discussions surrounding predictive digital twins remain fragmented and lacking a comprehensive resource. This gap becomes particularly pronounced in the academic world, where, as a university professor teaching a master's program course in digital twins, there arises a pressing need for a dedicated reference book to furnish students with a structured and in-depth exploration of predictive digital twins.The book fills the existing void in literature and academia, providing students, researchers, and practitioners with a valuable resource to enhance their understanding of this cutting-edge concept. The digital twin concept stands as a pivotal facilitator in the ongoing Industry 4.0 revolution, with one of its most significant advantages lying in its capacity to offer precise predictions.

  • Clinical Management of Pancreatic Cancer

    From Diagnosis to Palliative Care
    • 1st Edition
    • Takuji Okusaka + 1 more
    • English
    Clinical Management of Pancreatic Cancer: From Diagnosis to Palliative Care provides comprehensive guidance and support at every step of the pancreatic cancer journey, covering initial diagnosis and compassionate and holistic care. The book not only presents the latest advancements, including innovative surgical techniques, targeted therapies, radiotherapy approaches, and palliative care interventions, but also focuses on maintaining and improving patients' quality of life throughout their journey and incorporating palliative medicine and supportive care to alleviate symptoms and enhance overall well-being. Sections advocate for patient-centered care by emphasizing communication, shared decision-making, and tailored treatment approaches to individual needs and preferences.In addition, the book raises awareness about pancreatic cancer, its challenges, and the importance of early detection while also dispelling misconceptions and offering hope through informed management strategies. It serves as a bridge between research and clinical practice, offering researchers a broader perspective while also equipping clinicians with a valuable resource that enhances their knowledge, decision-making, and patient care skills.

  • Fetal Metabolic Programming in Obesity and Diabetes

    From Mechanisms to Preventive Therapy
    • 1st Edition
    • Luis Sobrevia
    • English
    Fetal Metabolic Programming in Obesity and Diabetes: From Mechanisms to Preventive Therapy describes the consequences of cellular and molecular aspects of maternal obesity (before and during pregnancy), diabetes mellitus (pregestational and gestational), and gestational diabesity (i.e., women with pre-pregnancy obesity that developed GDM). The book covers the clinical aspects of mothers and children and the protocols for treating these diseases during pregnancy. Since the patients' clinical information correlates with metabolic parameters at a cellular and systemic level, it covers several pieces of evidence, addressing the pathophysiology of obesity and diabetes in pregnancy.This is an important resource for health professionals, researchers, and postdocs in obesity diabetes, as well as public health, physiology, biochemistry, cell biology, cell physiology, cell metabolism, and clinical medicine.

  • Drug Discovery

    Traditional Approaches and Advanced Strategies
    • 1st Edition
    • Renren Bai
    • English
    Drug Discovery: Traditional Approaches and Advanced Strategies is a foundational monograph that connects established methodologies, cutting-edge technologies, and the transformative impact of AI and other emerging tools in the drug discovery landscape. Sections provide an overview of drug discovery and development, introducing current trends and the evolving landscape of the field, explore traditional approaches alongside advanced strategies, covering topics such as drug target discovery, lead optimization, and the revolutionary role of artificial intelligence in drug discovery, and investigate promising emerging technologies, including targeted protein degradation and innovative design strategies. Equipping readers with insights into the future of drug development, this is a vital resource for academic and industrial researchers, students, and professionals seeking to stay at the forefront of drug discovery. By integrating traditional methodologies with the latest advancements, this book not only enhances understanding but also inspires innovation. With practical case studies and real-world applications, it empowers researchers to effectively implement new technologies, ultimately improving the efficiency and success rates of their R&D endeavors.

  • Understanding Molecular Processes using Electrochemical Methods

    • 1st Edition
    • Ashis Kumar Satpati + 1 more
    • English
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.

  • Network Pharmacology

    Exploring New Horizons in Drug Discovery
    • 1st Edition
    • Veeranoot Nissapatorn + 4 more
    • English
    Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach—which examines the intricate interactions between disease targets and metabolites—offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.

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