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Academic Press

Molecular Insights into Proteinopathies
Increased Scope from Neurodegeneration to other Pathologies of the Brain
1st book:metaData.edition
Eva Žerovnik contributors.plusContributors
publicationLanguages:en
Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.
Handbook of Solar Cells
From Fundamentals to Recent Advances
1st book:metaData.edition
Naveen V. Kulkarni contributors.plusContributors
publicationLanguages:en
Handbook of Solar Cells: From Fundamentals to Recent Advances is a comprehensive, practical resource that enables the reader to understand the development of advanced solar cell technologies and materials. Coverage is clearly organized by solar cell type, taking the reader through the principles, theory, methodology, recent advances, challenges, and future prospects in each area, all of which are supported with case studies, supplementary data, clear definitions, learning objectives, and questions to test understanding.This handbook will be valuable to all those with an interest in solar cells, solar power plants, solar energy, and renewable energy, including advanced students, graduates, researchers, faculty, engineers, plant operators, R&D, and other industry professionals.
Diabetic Neuropathy
1st book:metaData.edition
Shahidul Islam
publicationLanguages:en
"Recent Therapeutic Targets for the Prevention and Management of Diabetic Complications: Neuropathy" covers recent research and therapeutic approaches of this diabetic complication for the management of diabetes. It is a detailed reference to understand the pathogenesis of diabetes to alleviate the overall complications of neuropathy to improve patient care. It is uniquely focused on the different aspects of neuropathy with a focus on the molecular and biological pathways (therapeutic target) to detect an early diagnosis to better manage the disease and improve patient care. The book is useful to anyone in the field particularly those who do research investigations, and day-to-day practice in the area of diabetes.
Drug Discovery
Traditional Approaches and Advanced Strategies
1st book:metaData.edition
Renren Bai
publicationLanguages:en
Drug Discovery: Traditional Approaches and Advanced Strategies is a foundational monograph that connects established methodologies, cutting-edge technologies, and the transformative impact of AI and other emerging tools in the drug discovery landscape. Sections provide an overview of drug discovery and development, introducing current trends and the evolving landscape of the field, explore traditional approaches alongside advanced strategies, covering topics such as drug target discovery, lead optimization, and the revolutionary role of artificial intelligence in drug discovery, and investigate promising emerging technologies, including targeted protein degradation and innovative design strategies. Equipping readers with insights into the future of drug development, this is a vital resource for academic and industrial researchers, students, and professionals seeking to stay at the forefront of drug discovery. By integrating traditional methodologies with the latest advancements, this book not only enhances understanding but also inspires innovation. With practical case studies and real-world applications, it empowers researchers to effectively implement new technologies, ultimately improving the efficiency and success rates of their R&D endeavors.
Fluid Dynamics with the Lattice Boltzmann Method
1st book:metaData.edition
Ilya Karlin contributors.plusContributors
publicationLanguages:en
Originating from the lattice Gas Automaton, LBM has reshaped the field with its straightforward approach and high efficacy. Despite its widespread use, navigating the scattered literature can be daunting for newcomers. Fluid Dynamics with the Lattice Boltzmann Method presents a clear path from novice to expert. This comprehensive guide bridges gaps in understanding, covering essential principles and exploring advanced topics like compressible flows and combustion. Authored by experts, this book consolidates diverse models and recent advancements, ensuring you're equipped to navigate the latest developments in computational fluid dynamics. Whether you're just starting out or aiming to stay ahead of the curve, this book is your essential companion in mastering LBM.
Nerve Growth Factor
From Neuron Development to Neurology
1st book:metaData.edition
Antonino Cattaneo contributors.plusContributors
publicationLanguages:en
Nerve growth factor: From Neuron Development to Neurology, the latest release in the Molecular Mediators in Health and Disease series, offers a complete guide to nerve growth factor (NGF) across health and disease. Sections cover key properties, the latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters discussing the brain, immune system, blood vessels, heart, reproductive organs, teeth, and lungs. NGF pharmacology is then considered, with a focus on NGF as a therapeutic agent.The final section of the book covers NGF across diseases, including Alzheimer’s disease, cancer, diseases of the eye, chronic pain, and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology, making it an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology, and other biomedical areas.
Aquatic Biodiversity
Theories, Approaches, and Future Directions
1st book:metaData.edition
Bryan L Brown contributors.plusContributors
publicationLanguages:en
Aquatic Biodiversity: Theories, Approaches, and Future Directions reviews the development of metacommunity ecology theory in aquatic systems. The book explores aquatic dispersal as a driver of community biodiversity, patterns, and processes. Considered a relatively new field, metacommunity ecology created a paradigm shift in the field of aquatic ecology by developing a novel, network-based theory that differences in connectivity throughout aquatic systems lead to predictable variations in the mechanisms of assembly for lentic and lotic communities. This book collates the cutting edge conceptual, theoretical, and empirical advancements of the field and its contributions to invasive species management, biomonitoring, and stream restoration.Written and edited by many of the key researchers contributing to the development of the field, this book is systematically structured for easy accessibility by diverse audiences. Introductory sections discuss the importance of spatial structure, dispersal dynamics in aquatic systems, the effects of disturbances, and eco-evolutionary dynamics. Latter chapters apply these theories by describing field experiments in lentic and lotic systems and highlighting the field's applications to stream restoration, invasive species monitoring, urban ecosystem management, and biomonitoring at varying spatial scales.As advancements and refinements to the field of metacommunity ecology develop, Aquatic Biodiversity presents the first compendium establishing its foundational theories and their applications in aquatic ecology. For this reason, it is an indispensable resource for students, researchers, community ecologists, and aquatic resource managers.
Marination
A Novel Technology to Improve the Quality and Safety of Foods
1st book:metaData.edition
Ioannis Savvaidis contributors.plusContributors
publicationLanguages:en
Marination: A Novel Technology to Improve the Quality and Safety of Foods presents the latest developments in marination as a method of intervention in providing an improvement in food quality and assuring the safety of perishable foods. Composed of 12 chapters, the title covers marination types and their applicability in various food types (fish/seafood, meats, plant-based fresh produce, dairy-based products). Besides presenting existing technologies to improve the quality of foods and extend shelf-life, the book also discusses marination as both a preservation technique and a technology to produce novel foods to consumers.Edited by a team of experts in the field, this book is a unique resource for researchers, scientists and industry personnel interested in natural techniques for preserving food and preventing the growth of food pathogens.
Cellular Therapies for Cancer Treatment
Advancements in Drug Delivery Strategies
1st book:metaData.edition
Arun Kumar Singh contributors.plusContributors
publicationLanguages:en
Cellular Therapies for Cancer Treatment: Advancements in Drug Delivery Strategies explores the innovative use of cellular therapy to combat cancer, placing an emphasis on state-of-the-art delivery approaches. By covering a variety of cellular therapies for cancer, such as stem cells, immune cells, and others, this book provides a comprehensive introduction to the field. It describes ways to deliver drugs that target cancer cells more efficiently, decrease off-target effects, and enhance therapy outcomes. Sections provide a brief overview of cancer cell biology, describe the need for advance drug delivery systems, and address challenges and future directions.The book also goes into the ideas behind cellular therapies and how they may overcome drug resistance and make existing cancer treatments more effective. By elaborating on the value of diversity and inclusion in cancer research and treatment, the book also emphasizes the importance of all patients having equal access to innovative therapies. All things considered, this book is a great tool for researchers, doctors, and students in the cancer treatment sector.
Pediatric Substance Exposure
1st book:metaData.edition
Ju Lee Oei
publicationLanguages:en
Pediatric Substance Exposure is a crucial resource for medical practitioners focusing on the long-term management of children exposed to addictive substances during pregnancy. It provides guidance on supporting families affected by substance abuse, starting with a comprehensive overview of epidemiology and global policy. The book examines various substances and their impact on children, discussing fetal management, infant and child care, and addressing family needs as the child grows. Beyond the basics, the book reviews social aspects, future research, and policy needs. Clinicians and researchers will find it invaluable for evidence-based decision-making and optimal treatment strategies.

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