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  • River Dolphins and Larger Toothed Whales

    Ridgway and Harrison's Handbook of Marine Mammals, Volume 3
    • 1st Edition
    • Thomas Allen Jefferson + 1 more
    • English
    River Dolphins and Larger Toothed Whales, Volume Three in Ridgway and Harrison's Handbook of Marine Mammals, consists of species review chapters written by global experts on brackish and freshwater dolphin species and larger toothed whales. Each chapter includes a description of the species that is followed by sections on distribution and abundance, anatomy, physiology, behavior, ecology, reproduction, parasites and diseases, and the impacts of human activities on the species. This series was founded to help scientists, conservationists, and informed laypersons alike find definitive reviews on all the world's living whales, dolphins, porpoises, seals, sea lions, sea cows, marine otters, and bears.Some of the world's most beautiful, intelligent, and highly adapted mammals inhabit our seas and oceans and have stirred the human imagination for many centuries. As our knowledge of marine mammals grows, the need exists for a reliable and complete reference to the ecology and biology of these fascinating creatures. This book addresses this important need.

  • Lifestyle Epigenomics

    • 1st Edition
    • Ana B Crujeiras
    • English
    Lifestyle Epigenomics, a new volume in the Translational Epigenetics series, comprehensively details the interplay between lifestyle factors and epigenetic modifications associated with the onset of noncommunicable diseases and aging, shedding light on potential preventive and therapeutic strategies for disease from an epigenomics perspective. Here, more than 35 international experts in the field consider how lifestyle choices or habits can condition or prevent disease, along with tools for new research, from bioinformatics methodology to non-invasive sampling.Early, foundational chapters are followed by all-inclusive sections on epigenetic machinery in health and disease; dietary factors and epigenetics; adiposity and physical activity and epigenetics; psychological stress, social environment, toxins and contaminants exposure effects on epigenetics; and transgenerational and childhood epigenetics. To support understanding, each chapter includes a summary and key points lists, terms and definition, as well as research case studies outlining core components of recent studies, detailing their conditions, research techniques involved, and outcomes.

  • Beer in Health and Disease Prevention

    • 2nd Edition
    • Victor R. Preedy
    • English
    Just as wine in moderation has been proposed to promote health, research is showing that beer – and the ingredients in beer – can have similar impact on improving health, and in some instances preventing disease. Beer in Health and Disease Prevention, 2nd Edition addresses both the benefits and concerns associated with consumption of beer and beer ingredients on cancers, cardiovascular disease, antioxidant benefits, and other health related concerns. It offers a holistic view from beer brewing to the isolation of beer-related compounds.Beer in Health and Disease Prevention, 2nd Edition continues to be the single most comprehensive volume needed to understand beer and beer-related science. Presenting both the concerns and problems of beer consumption as well as the emerging evidence of benefit, this book offers a balanced view of today's findings and the potential of tomorrow's research. This is an essential reference for researchers studying alcoholic beverages, beer brewing, nutrition, and public health. Dieticians and clinicians, as well as those working in the beer brewing industry, will also benefit from this invaluable resource.

  • Mangrove Ecosystem Dynamics

    • 1st Edition
    • Daniel M Alongi
    • English
    Mangrove Ecosystem Dynamics presents a comprehensive account of the various functions of mangrove habitats, from spatial dynamics of intertidal ecosystems to nutrient and biogeochemical cycling in sediments, tidal and coastal waters, and dependent species. This process-oriented approach is necessary to further understand the role of these dynamic habitats in the coastal ocean, and as a next step towards developing adequate strategies for mangrove conservation, management, and sustainable use.Written by a leading expert in mangrove biology and tropical marine ecology, this book takes an energetics approach to summarize the latest developments and knowledge in the field of mangrove ecology. Initial chapters discuss the fundamentals of intertidal environments and the spatial and temporal dynamics of mangrove habitats. Latter chapters address recent advances in food web energetics in tidal waters, exploring benthic invertebrate, planktonic, fish, and arboreal food webs. Final sections detail decomposition of organic matter, nutrient cycling, and carbon sequestration.Mangro... Ecosystem Dynamics addresses rapidly emerging and vital issues of climate change, blue carbon, sustainable management and restoration, and the connectivity and interdependence between mangroves and other coastal habitats and species. This new work offers a comprehensive functional view of the current and future state of mangrove ecosystems that will greatly benefit coastal and marine biologists, resource managers, conservationists, and students alike.

  • Cholinergic Drugs for Alzheimer's Disease

    From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions
    • 1st Edition
    • Cheorl-Ho Kim
    • English
    Cholinergic Drugs for Alzheimer’s Disease: From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions addresses the urgent need for advanced resources in neuropharmacology. The first section presents mechanistic insights into cholinergic drugs, current hypotheses for Alzheimer’s Disease progression, neurotransmitter systems, receptor biology, and the evolution of acetylcholinesterase inhibitors, including hybrid and multi-target drugs. It also covers clinical status, neuromuscular blockers, non-adrenergic neurotransmitters, protein kinase inhibitors, inflammation modulation, NMDA antagonism, biomarkers, and AI-assisted drug discovery.The second section explores natural alkaloidal and non-alkaloidal compounds, molecular docking, SAR analysis, and daily consumable resources, with the third section investigating marine-derived AChE inhibitors, dual- and multi-target drug concepts, and emerging therapeutic compounds. This book equips the scientific community with a robust foundation for understanding and innovating in Alzheimer’s Disease therapy. By integrating molecular biology, pharmacology, and computational approaches, it empowers researchers and clinicians to address treatment challenges, optimize drug design, and leverage natural products for multifactorial intervention.

  • Body-on-a-Chip

    Essentials and Applications
    • 1st Edition
    • Anthony Atala + 1 more
    • English
    Body-on-a-Chip: Essentials and Applications provides the reader high-quality information, in a single resource, that is necessary to explore the use of BOC systems from design and development to testing and personalized medicine, to medical research and diagnostics. BOC systems can recapitulate native tissue/ organ architecture, diffusion kinetics of drugs physiological flow conditions etc., similar to what would happen in the body, they are particularly powerful in predicting human efficacy prior to clinical testing of a drug, determining potential toxicity, or in clinical studies to test underlying mechanisms or action or adverse effects. With recent advancements in high-throughput analysis systems and artificial intelligence, it has also become possible to screen several drugs at a time.

  • Public Engagement and Ethics Communication in Brain Research, Innovation, and Health

    • 1st Edition
    • Volume 9
    • English
    Public Engagement and Ethical Communication in Brain Research, Innovation, and Health, Volume Nine in the Developments in Neuroethics and Bioethics series, provides a comprehensive overview of various understandings of neuroscience and (neuro)ethics communication across research, policy, and society. Specific chapters in this new release include Neurohype Across Borders: How Media Narratives Shape Public Perception of Neurotechnology in English- and Spanish-Speaking Countries, Physicians’ Resistance Towards Pandemic Public Health Policies in Romania: Navigating Misinformation, Ethical Challenges, and Responsibility in Science Communication, Foresight Scenarios as Communicative Instruments in Anticipatory Neuroethics, and much more.Additional chapters include Draw closer to me: Participatory visual storytelling to include socio-cultural perspectives in neuroethics and policymaking, Against the Narrative of the Insufficiency of Human Rights on the Neurorights Discourse, Reflective accounts from collaborative neuro-oncology research: perspectives from patient partners and researchers, Responsible conceptualization in research and innovation, Anticipating Polarization: Public Discourse and the Unpreparedness of Neuroethics Communication, Shared Responsibility for Communicating Neuroscience Research: A Case Study for Spinal Cord Injury, and much more.Featured topics include creative and participatory approaches to (neuro)ethics communication, the impact of narratives on public perception and science policy, the importance of responsible communication in neuroscience, and the dynamics between patient partners and researchers. The volume also addresses cross-cultural perspectives and focuses on comparative case studies of current emerging neuroscience research and neurotechnologies across countries.

  • Cytokine-Based immunotherapy Part B

    • 1st Edition
    • Volume 401
    • English
    Cytokine-Based immunotherapy: Part B, Volume 401 delves into the intricate world of cytokines, the vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. Chapters cover Cytokine-based immunotherapy in pancreatic cancer, IL-33 and its pleiotropic role in cancer, Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity, Cytokine network in immunosuppression and tumor development in glioblastoma, The Double-Edged Role of Interferon Gamma in Cancer Immunity, and much more.An additional section covers Engineering Interleukin-10 for Therapeutic Applications, IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases. Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 118
    • English
    Magnetic resonance now has a history exceeding 70 years. Not only has the range of applications of magnetic resonance-based techniques grown exponentially but so too has the literature. Consequently, a distillation and synthesis of the literature is in itself an extremely important research tool, providing an efficient means to take newcomers to the research frontiers and keeping experienced researchers aware of contemporary practice.Since 1968 Annual Reports on NMR Spectroscopy been at the vanguard of reviewing the magnetic resonance literature. Annual Reports on NMR Spectroscopy covers magnetic resonance in all its forms, including theory, experiment, applications, and interconnections with other techniques. It also provides the opportunity to make coherent aspects of magnetic resonance that were scattered and opaque. Historical articles are also welcomed.Potential authors are encouraged to consult with the Editor.William S. PriceWestern Sydney University, NSW, Australiae-mail address: w.price@westernsydne...

  • Natural extracellular vesicles: a new nanomedicine for cancer

    • 1st Edition
    • KN ArulJothi + 5 more
    • English
    "Natural-Derived Extracellular Vesicles: Innovations in Nanomedicine" explores the potential of natural-derived extracellular vesicles (NDEVs) as next-generation tools in therapeutic applications. Shifting the focus from mammalian-derived EVs, this book highlights plant, fungal, bacterial, and algal sources, promoting a sustainable and biocompatible approach to drug delivery and disease modulation. The content emphasizes the unique properties of NDEVs in cancer therapy, immunomodulation, and regenerative medicine, addressing the limitations of conventional therapies by enhancing drug bioavailability and reducing off-target effects. It also provides insights into underexplored sources and practical guidance on safety, scalability, and regulatory considerations. For the academic audience, this book serves as a comprehensive resource that bridges nanotechnology and biomedical sciences. It equips researchers, clinicians, and pharmaceutical scientists with consolidated knowledge and experimental techniques, empowering them to explore the evolving frontiers of precision-driven therapeutics rooted in nature.

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