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Academic Press

  • Immunomodulators - Part A

    • 1st Edition
    • Volume 151
    • English
    Immodulators, Volume 151 explores the pivotal role immodulators play in regulating immune responses for health and disease management. The book provides an in-depth overview of various classes of immunomodulatory agents, including biologics, small molecules, natural compounds, and synthetic drugs, examining their mechanisms of action and therapeutic applications. Chapters in this new release include Marine-Derived Polysaccharides and Peptides as Next-Generation Immunomodulators: Molecular Mechanisms, Therapeutic Potential, and Translational Challenges, Advances in Immunomodulation: From Dietary Influence to Computational Precision, iPSC-derived immunotherapy for Tau and Alzheimer's disease, and much more.Additional sections cover Antibodies targeting amyloid-β and Tau oligomers in Alzheimer's Disease, Biosimilars: Antibody and Nanobody Based Therapeutic Approaches Towards Protein Misfolding Diseases, Immunomodulator drugs: mechanisms of action and systemic effects, Microbiome and microbial products as immunomodulators: implication for gastrointestinal cancers, Integration of Network pharmacology, docking, and dynamics analysis to investigate the immunomodulatory activity of Pongamia pinnata, Transcriptomic Insights into Epigenetic and Immunomodulatory Roles of Nuclear Histone Genes in Bladder Cancer: A bioinformatics Approach, Utilizing DREIMT Database for Drug Prioritization in Immunomodulatory Therapy for Psoriasis and Psoriatic Arthritis, and many additional topics.

  • Comparative Fish Immunology

    • 1st Edition
    • Volume 42
    • English
    Integrative Fish Biomechanics, Volume 42 in the Fish Physiology series, highlights new advances in the field, with this volume presenting insightful chapters written by leading experts. Covering a broad range of topics, this edition explores the evolution and function of immune systems in fish, with particular attention to both innate and adaptive immune mechanisms across diverse aquatic species.Chapters examine adaptive immunity in jawless vertebrates and the unique VLR system, the role of antimicrobial peptides in teleost infections, and the use of zebrafish as a model for studying innate immune responses. Additional contributions explore pharyngeal mucosal lymphoid structures, the evolutionary origins of germinal centers in fish, and mechanisms of antigen presentation in teleosts.Other chapters address microbiota–host immune interactions, emerging insights into teleost neuroimmunology, and the modulation of immune function through behavioral fever. Together, these contributions provide a comprehensive overview of current discoveries and evolving perspectives in fish immunology, offering valuable insights for researchers, immunologists, and aquatic biologists interested in the physiology and immune biology of fishes.

  • Brain Rehabilitation in Psychiatric Disorders

    • 1st Edition
    • Volume 301
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Autophagy – Part A

    • 1st Edition
    • Volume 403
    • English
    Autophagy – Part A, Volume 403 explores the fundamental biological process of autophagy. Beginning with the historical discovery and molecular mechanisms of autophagy, the book delves into its regulation, physiological roles, and significance in maintaining cellular homeostasis. Chapters in this new release include Ciliophagy: Maintaining Primary Cilium Homeostasis to Prevent Cilium-Related Diseases, Unraveling the interplay of glycolysis, lactylation, and autophagy, Autophagy and Type 2 Diabetes: Bridging the Gap in Metabolic Health, Autophagy in Cancer Cachexia: From Mechanisms to Therapeutic Opportunities, Glycophagy: A Selective Autophagy Pathway for Glycogen Degradation, Role of Autophagy in Adipose Tissue: Implications for Metabolic Health, and more.

  • 2D and 3D Cellular Screening Models and AI Guided Analysis

    • 1st Edition
    • Volume 204
    • English
    2D and 3D Cellular Screening Models and AI Guided Analysis, Volume 204 explores the development, application, and comparative benefits of 2D monolayer cultures and 3D organoids, spheroids, and tissue-engineered constructs for biomedical research and drug discovery. Chapters in this new release include High throughput CellTiter-glo viability assessment, Assessing viability of cancer cell spheroids in 3D drug screening, 3D killing assay of cancer spheroids by cytotoxic T lymphocytes in anchored microfluidic droplets, Use of micropatterning for 3D cell culture, Use of microfluidic chip devices for assessing the effect of radiation on 3D cell culture models, and much more.Additional chapters cover A 3D model for assessing regulated cell death modalities, YOLO detection model for Cell Viability assessment, Bioinformatics and AI/ML approaches using multi-omics data to accelerate diagnosis and delivery of precision care, Automated image analysis and machine learning for the assessment of mitochondrial membrane potential, Assessing cancer cell heterogeneity in patient-derived tumoroids, Assessment of lysosomal drug sequestration and release using fluorescence microscopy, Assessment of T cell toxicity in ex-vivo models of cancer, Three-dimensional Organoid Screening using Leica Thunder Microscope, Using vascularized organoids-on-chip for assessing systemic drug delivery, and many more interesting and timely topics.

  • Advances in Imaging and Electron Physics

    • 1st Edition
    • Volume 237
    • English
    Advances in Imaging and Electron Physics, Volume 237 merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. Chapters in this new release include Stochastic geometry with applications in materials science, Morphological models of random media, Grain models and application to microstructure simulation, MCMC algorithms for model parameterization, Tessellations models, Tesselation models, Fast simulation of tessellation models using Eikonal equation, Applications to Image Processing, Synthesis of Training Images for Supervised Learning Problems, and Segmentation Methods Based on the Eikonal Equation.

  • Artificial Intelligence for Multi-omics Analysis Part B

    • 1st Edition
    • Volume 222
    • English
    Artificial Intelligence for Multi-omics Analysis Part B, Volume 222 in the Progress in Molecular Biology and Translational Science series, highlights recent advances, with this new volume presenting chapters on a variety of topics, including Artificial Intelligence in multi-omics analysis of small molecule drug discovery, AI in multi-omics analysis in antimicrobial resistance, Artificial Intelligence and multi-Omics Approach in Vaccine Development, Artificial Intelligence in multi-omics Analysis of heart diseases, Artificial Intelligence in multi-omics Analysis of Kidney Diseases, Artificial Intelligence in multi-omics Analysis of Gastrointestinal Diseases, AI in multi-omics analysis in Stem cell research, and AI in multi-omics analysis in cancer, and more.Additional sections cover AI in multi-omics analysis in obstructive lung diseases, AI in multi-omics analysis in neurodiseases, AI in multi-omics analysis in autoimmune diseases, AI in multi-omics analysis of liver diseases, AI in multi-omics analysis of COVID-19 patient data, and AI in multi-omics analysis of Type 2 diabetes.

  • Structural Studies of Amyloid-Forming Peptides

    • 1st Edition
    • Volume 729
    • English
    Structural Study of Amyloid-β, Volume 729 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics such as the Extraction of Amyloids from Neurodegenerative Disease Tissues for Structural Analysis, Cryo-EM Structure Determination of Amyloid Fibrils: Methodology, Insights, and Practical Tools, Methods for studying molecular architecture of Ab aggregates in tissues using cryo-ET, Cryo-EM methods to study binding between amyloid fibrils and chemical compounds or ligan, Dynamics studies of side-chains and hydration shells in amyloid-beta fibrils using deuterium and oxygen-17 solid-state NMR, and much more.Additional chapters cover the Technical aspects of pressure jump NMR applied to the study of Abeta and protein oligomerization, Characterizations of the beta-amyloid-membran... interaction intermediates, Time-resolved solid-state NMR studies of oligomer formation, Methods for characterizing the individual filament structures of amyloid peptide assemblies using atomic force microscopy, Single-molecule fluorescence spectroscopy and imaging on heterogeneous amyloid beta aggregation, Two-dimensional FT-IR methods on amyloid aggregation and folding pathways, and much more.

  • Epigenetic Regulation of Cancer - Part E

    • 1st Edition
    • Volume 400
    • English
    Epigenetic Regulation of Cancer, Part E, Volume 400 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic regulation of cancer, Phytochemicals with epigenetic properties and their role in melanoma therapy, Epigenetic Insights of MicroRNAs: Pioneering Cancer Detection via Advanced Biosensors, Epigenetic Regulation of Autophagy in Cancer: A Double-Edged Sword in Tumor Progression and Therapy Resistance, Epigenetic Regulation via Histone Modifications in Ovarian Cancer, The current findings and potential applications of breast cancer epigenetics, and much more.Other chapters cover the Application of bioinformatics and data science in studies of cancer epigenetics, and much more.

  • Cytoskeletal Proteins in Neurodegenerative Diseases

    • 1st Edition
    • Volume 150
    • English
    Cytoskeletal Proteins in Neurodegenerative Diseases, Volume 150 covers the pivotal roles that cytoskeletal proteins play in the onset and progression of neurodegenerative disorders. The book explores the structure, function, and dynamics of key cytoskeletal components—including microtubules, actin filaments, and intermediate filaments—and examines how their dysfunction contributes to diseases such as Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis (ALS). Chapters in this new release include Cytoskeletal proteins regulates Tau in Alzheimer's Disease, "Sticks with whips in neurodegenerative diseases: On the roles of intrinsic disorder in (dis)function of cytoskeletal proteins", Glial Fibrillary Protein is potential biomarker For AD, and much more. Additional chapters cover Cytoskeletal disintegration in cardiovascular disease-related neurodegeneration, Cytoskeletal Proteins in Neurodegeneration, Extracellular matrix degradation proteins in Neurodegenerative disease, GPCRs regulates Cytoskeletal remodeling in microglia, Understanding the impact of cytoskeleton disruption on synaptic plasticity in Alzheimer's Disease, Chemokine receptors modulates Cytoskeletal proteins in Alzheimer’s disease, Cytoskeletal Intermediate Filament proteins in Neurodegeneration, Mechanism of tau proteins differentially regulating the motility of different families of kinesin motors, The Quest to Restore Neuronal Structure: Targeting Cytoskeletal Proteins in Neurodegenerative Diseases, and many more timely topics.

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