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Academic Press

Current Topics in Cellular Regulation
1st Edition
Volume 16
Bernard L. Horecker + 1 more
English
Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation. This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynt... multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesiz... and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation. This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.
Experimental Manipulation of Gene Expression
1st Edition
Masayori Inouye
English
Experimental Manipulation of Gene Expression discusses a wide range of host systems in which to clone and express a gene of interest. The aims are for readers to quickly learn the versatility of the systems and obtain an overview of the technology involved in the manipulation of gene expression. Furthermore, it is hoped that the reader will learn enough from the various approaches to be able to develop systems and to arrange for a gene of particular interest to express in a particular system. The book opens with a chapter on the design and construction of a plasmid vector system used to achieve high-level expression of a particular phage regulatory protein normally found in minute amounts in a phage-infected bacterial cell. This is followed by separate chapters on topics such as high-level expression vectors that utilize efficient Escherichia coli lipoprotein promoter as well as various other portions of the lipoprotein gene Ipp; DNA cloning systems for streptomycetes; and the design and application of vectors for high-level, inducible synthesis of the product of a cloned gene in yeast.
A Course in Probability Theory
2nd Edition
Kai Lai Chung
English
This book contains about 500 exercises consisting mostly of special cases and examples, second thoughts and alternative arguments, natural extensions, and some novel departures. With a few obvious exceptions they are neither profound nor trivial, and hints and comments are appended to many of them. If they tend to be somewhat inbred, at least they are relevant to the text and should help in its digestion. As a bold venture I have marked a few of them with a * to indicate a "must", although no rigid standard of selection has been used. Some of these are needed in the book, but in any case the reader's study of the text will be more complete after he has tried at least those problems.
Immunointervention in Autoimmune Diseases
Papers Based on an International Meeting in Paris, France, in June 1988
1st Edition
J. F. Bach
English
Immunointervention in Autoimmune Diseases is a collection of papers presented at the 1988 International Meeting by the same title, held in Paris, France. This text contains 21 chapters and begins with surveys of the role of antigen in autoimmune responses and the moving boundaries between physiology and pathology of immunity. The succeeding chapters deal with the regulation, immunosuppressive therapy, infections, and immunointervention of autoimmune disorders. These topics are followed by discussions of specific immunosuppressive therapy for a particular disease, including type I diabetes, T-cell leukemia, and systemic lupus erythomatosus. This work also explores the principles of allograft, the use of monoclonal antibody, and OKT3. The remaining chapters consider the maintenance of autoimmunity and the risk/benefit in immunointervention for autoimmune diseases. This book will prove useful to immunologists, pathologists, physiologists, and researchers.
Behavior of Nonhuman Primates
Modern Research Trends
1st Edition
Volume 3
Allan M. Schrier + 1 more
English
Behavior of Nonhuman Primates: Modern Research Trends, Volume 3 provides information pertinent to research on behavior of nonhuman primates. This book presents the knowledge of the social development of rhesus infants and compares with data on other species. Organized into four chapters, this volume begins with an overview of the interspecies differences in the social influences affecting young primates. This text then examines the nature of the interactions between the infant and its various social companions, wherein each type of social companion may interact with the infant in a number of ways. Other chapters consider the nature of the social organization, which may be presumed to have been shaped by the ecological pressures of the natural habitat. This book discusses as well the color vision and visual acuity in different animals. The final chapter deals with the aspects of primate hearing. This book is a valuable resource for students and research workers.
Current Topics in Bioenergetics
Volume 10
1st Edition
D. Rao Sanadi
English
Current Topics in Bioenergetics, Volume 10 provides information pertinent to the developments in the study of dynamic mechanisms in functioning muscle by following fluctuations in kinetic states. This book explores the method that permits analysis of cyclic rotational motions in cross-bridge formation and has considerable potential in other bioenergetics systems. Organized into six chapters, this volume begins with an overview of the structure and function of muscles. This text then examines the bioenergetic aspects of nitrogen fixation. Other chapters consider one aspect of the regulation of the in vivo activity of organelles, namely, the regulation of mitochondrial activities at the level of substrate. This book discusses as well the status of the controversial findings on the proton–oxygen ratios in mitochondria and the mechanism of H+ pumping in oxidative reactions. The final chapter deals with the usefulness of bacterial mutants in the study of cell metabolism. This book is a valuable resource for biologists and biochemists.
Clinical Immunobiology
1st Edition
Volume 3
Fritz H. Bach + 1 more
English
Clinical Immunobiology, Volume 3 covers a variety of methods used for assaying the immune status of an individual. This volume is composed of 21 chapters and begins with a presentation of the background and issues to which clinical tests would be applied. The succeeding chapters outline the methodological procedures used in the analyses. Other chapters present some examples of the kinds of data that can be generated with the procedures used and provide guidelines for interpretation of the tests. The remaining chapters discuss the value of the immunological test procedures in differential diagnosis and analysis of diseases. These chapters also explore the usefulness of these procedures in prognosis of disease and the consequences of immunological manipulation undertaken for treatment or prevention of disease. This book will be of great value to clinical immunobiologists, biochemists, and researchers.
Current Topics in Cellular Regulation
1st Edition
Volume 23
Bernard L. Horecker + 1 more
English
Current Topics in Cellular Regulation: Volume 23 is a collection of papers that discusses pyruvate carboxylase, the regulation of carbohydrate metabolism, and the plasma membrane ATPase of fungi or plants. Other papers deal with adrenergic control of phosphofructokinase, protein phosphatase, as well as the regulation of polypeptide precursors of mature mitochondrial proteins. One paper explains the three dimensional structure of pyruvate carboxylase and its reaction mechanism. Electron microscopic analyses show that four monomers of pyruvate carboxylases isolated from vertebrate sources form a tight tetrahedron-like structure. Another paper describes the regulation of fructose 2,6-bisphosphate concentration in the liver and of the enzymes that are responsible for its metabolism, and the mechanism involved in fructose, particularly in the regulation of 6-phosphofructo-1-ki... and fructose-1,6-bisphos... activity. The paper also explains the role of this effector in the regulation of hepatic carbohydrate metabolism. One paper deals with the different levels of biological organization (whole cells, isolated plasma membranes, and purified enzyme) that characterizes the plasma membrane ATPase of fungi and plants as a novel type of proton pump. The collection can prove useful for biologists, microbiologists, students, and professors of biology and biophysics.
Hormones
1st Edition
Anthony W. Norman + 1 more
English
Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.
Developments in Statistics
1st Edition
Volume 3
Paruchuri R. Krishnaiah
English
Development in Statistics, Volume 3 is a collection of papers that deals with asymptotic expansions in parametric statistical theory, orthogonal models for contingency tables, statistical concepts in economic analysis, and an exposition of path analysis. One paper presents an inference model based on a sample of independent identically distributed observations to arrive at a general statistical theory founded on asymptotic methods. Another paper discusses the applicability of statistical concepts to economics and related areas, with emphasis on not-so-obvious applications (known as utility and expected loss). The paper explains information theory concepts for the measurement of income inequality, intergenerational occupational mobility, as well as to first- and second-order moments of univariate and bivariate distributions (such as measurements applied to the cost of living and of real income). One paper notes that the starting point in path analysis is a linear predictor (in the least-squares sense) for one random variable in terms of a number of others. The paper adds that the work of Koopmans and Hood (1953) on econometrics is part of the starting point. Statisticians, economists, mathematicians, students, and professors of calculus or advanced mathematics will surely appreciate the collection.

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