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Academic Press

  • Advances in Lipid Research

    • 1st Edition
    • Volume 10
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 10 is a six-chapter text that is devoted to several special areas of lipid research, including significant progress in established areas of interest in the field. The introductory chapter surveys the application of electron microscopic techniques to the analysis of plasma lipoproteins. The subsequent chapter deals with the possible modification of reticuloendothelial functions by lipids and the role of lipids in cellular, humoral, and immune responses. These topics are followed by discussions of the microsomal enzymes of sterol biosynthesis and the enzymatic synthesis and degradation of glycerol lipids, which contain ether bonds. The remaining chapters focus on lipid neurochemistry. These chapters specifically examine particular brain lipids, such as fatty acids, phospholipids, sphingolipids, galatosyl lipids, and sterols. A discussion of lipids of the entire nervous system and their variation with age is also included. This book will prove useful to lipids chemists, biochemists, and organic chemists.
  • Fundamentals of Temperature Control

    • 1st Edition
    • William K. Roots
    • English
    Fundamentals of Temperature Control focuses on theoretical foundations and principles involved in temperature control. The book first offers information on thermal-process representation and response. Discussions focus on response to damped harmonic inputs, principle of superposition, bode diagrams, ramp, step, and impulse functions, harmonic response, electrical analogs, basic equations, and thermal conductivity. The text then examines common thermal elements and open-loop temperature control. The publication ponders on closed-loop temperature control and the dynamics of discontinuous temperature control. Topics include dynamics in the phase plane and time domain, dynamic analysis, closed-loop control, secondary feedback, and cooling processes. The manuscript then examines quasi-continuous and continuous temperature control, as well as quasi-continuously controlled process behavior in the time domain and quasi-continuously controlled process behavior in the phase plane. The text is a vital source of data for researchers interested in the fundamentals of temperature control.
  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 6
    • Norman J. Lass
    • English
    Speech and Language: Volume 6, Advances in Basic Research and Practice is a collection of papers that discusses pathology, theories, and clinical issues related to language and speech. Some papers describe auditory discrimination and intervention techniques for articulatory defects, assessment of auditory disorders, phonological systems of deaf speakers, as well as speech and language characteristics of aging persons. Other papers discuss issues in language and cognitive assessment of black children, distortions of the supralaryngeal vocal tract, the structure of the human tongue, transformation of the acoustic signal into speech, and methods to estimate glottal volume velocity waveform properties. One paper suggests guidelines that investigators should be aware of before giving any speech discriminating tests. These guidelines include the following: use of age appropriate tests, use of culturally unbiased tests, adaption of intrapersonal testing procedures, and utilization of recorded stimulus presentation. Another paper reviews auditory processing deficits associated with brain damage and the considerations applicable to the assessment of such disorders. It also suggests treatment planning. One paper concludes that the phonological structure of a fluent speech requires that the listener employ higher level sources of knowledge while making phonetic decisions. Linguists, speech pathologists., psychologists, speech therapists, neurologists, neuropsychologists, and neurolinguists will find the collection highly relevant.
  • Immunological Tolerance

    A Reassessment of Mechanisms of the Immune Response
    • 1st Edition
    • Maurice Landy + 1 more
    • English
    Immunological Tolerance: A Reassessment of Mechanisms of the Immune Response presents the basic biological phenomena of immunological tolerance. This book discusses immunology as a critical field for the analysis of molecular features of mammalian cell genetics, biosynthesis, differentiation, and interactions among cell types. Organized into six chapters, this book begins with an overview of the relationship between antigen structure and its ability to induce tolerance. This text then examines the essentiality of antigen for the proliferation of activated antibody-forming clones and discusses the role of antibody in homeostasis and suppression. Other chapters consider the restoration and transfer of immunological responsiveness by thoracic duct lymphocytes. This book discusses as well the distribution of antigen in tissues and cells. The final chapter deals with the origin of carrier antibody and the significance of maternal transfer of antibodies and antigens. This book is a valuable resource for immunologists, microbiologists, scientists, and clinicians.
  • Structure and Functions of Contractile Proteins

    Revisions, Additions, and a Foreword to the English-Language Edition Prepared by the Author
    • 1st Edition
    • Boris F. Poglazov
    • English
    Structure and Functions of Contractile Proteins focuses on the analysis of problems on the structure and functions of contractile proteins in which substantial progress has been achieved. The book first offers information on the protein constitution of myofibrils and myosin, including adenosinetriphosphat... activity, reaction with actin, and myosin molecule. The text also ponders on the polymerization of actin, tropomyosin, and the theory of contraction. Discussions focus on model experiments and molecular basis of contraction; structural interrelations of muscle proteins; features of the process of polymerization of actin; and size of the actin molecule. The text elaborates on the contractile proteins of the elementary motor structures of cells, as well as the chemical composition and physicochemical and enzymic properties of flagella and cilia; achromatin apparatus and movement of chromosomes; and structure of the flagella and cilia. Motor apparatus of bacteriophage and features of the movement of protoplasm and the mechanism of permeability are also discussed. The manuscript is a reliable source of data for readers interested in the structure and functions of contractile proteins.
  • Immunological Methods

    • 1st Edition
    • Ivan Lefkovits + 1 more
    • English
    Immunological Methods a compendium of basic research techniques being used in one of the largest immunology research institutes, the Basel Institute for Immunology, with particular emphasis given to new methodology. The procedures have been described by individuals judged to be highly expert in their specialties. In many instances the methods developed or adapted to unique uses by the contributors have not previously been described in detail. The book contains 34 chapters covering techniques for detection, isolation, and purification of antibodies (including dansylation, two-dimensional chromatography, isoelectric focusing, polyacrylamide gel electrophoresis, and isotachophoresis); measurement of equilibrium constants (equilibrium dialysis, filtration, and sedimentation); and isotope and fluorescent labeling and detection of cell-surface components. Techniques such as isotope laboratory maintenance; chemical modification of proteins, haptens, and solid supports, and haptenation of viable biological carriers; production of antisera against allotypes and histocompatibility antigens and production of antibody with clonai dominance; histocompatibility and MLR testing; and cell separation by haptenated gels and by velocity sedimentation of rosette-forming cells are also discussed. Other chapters cover detection of antibody-secreting and alloantigen-binding cells; immune responses in vitro and their analysis by limiting dilution; production of T-cell factors; hybridoma production by cell fusion; maintenance of cell lines and cloning in semisolid media; and the mathematical analysis of immunological data.
  • Advances in Lipid Research

    • 1st Edition
    • Volume 8
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 8 covers the significant progress in understanding the lipid chemistry and biochemistry of plants and animals. This volume contains seven chapters and begins with a discussion of the various aspects of cholesterol turnover in man and the possible mode of action of hypocholesterolemic regimens. The next chapters deal with the arterial composition and metabolism, with particular emphasis to esterified fatty acids and cholesterol, as well as the important role of essential fatty acids in mammalian development, health, and disease. A chapter emphasizes the participation of lipids in membrane structure. The remaining chapters explore the chemistry and biochemistry of phospholipids and glycolipids. These chapters also consider rumen metabolism and the surface chemistry of lipids. This book will prove useful to biochemists, organic chemists, physicians, and researchers.
  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 1
    • Norman J. Lass
    • English
    Speech and Language: Volume 1, Advances in Basic Research and Practice is a compendium of papers that discusses the processes and pathologies of, as well as applies theories and clinical issues to, speech and language. Some papers discuss perception of speech in early infancy, the problems faced by speech clinicians, and the anatomy of the perioral motor system. Based on data compiled on the infant's perception of speech sounds, one paper notes that human infants discriminate depending on fine temporal and frequency changes in a complex auditory array. Infants also show perceptual constraints while listening to speech characterized as adult- like; they are also predisposed to perceive certain speech-sound categories such as vowel and fricative categories. One paper examines the suggestion of Kent (1976) that "acoustic characteristics of children's speech...hold the promise of sensitive methods for the study of speech maturation and developmental disorders." This investigation involves the following: the recent attempts at multidimensional analyses of speech and perception; a measure of perceptual contrast; and results of feature comparison efforts. The compendium is well suited for linguists, ethnologists, psychologists, and researchers whose works involve linguistics, language learning, communications, and syntax.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 32
    • Earl R. Stadtman + 2 more
    • English
    Current Topics in Cellular Regulation: Volume 32 is a collection of papers that discusses the role of GTP-binding proteins in signal transduction, the activation of cholera toxin by ADP-ribosylation factors, and the signal transduction by the colony-stimulating factor-1 receptor. Other papers explain the secretory granule, the mechanism of stimulus-secretion coupling, calcium pumps in the plasma and intracellular membranes, as well as the protein phosphorylation in translational control. One paper proposes a linkage between the multimeric structures and cytoskeletal elements to bridge the signal transducing systems and the cytoskeletal network. Another paper describes the signaling mechanisms utilized by CSF-1R, the similarities, and differences when compared to other receptor tyrosine kinases (RTKs). The paper explains in detail the mechanism of ligand-induced kinase activation, and also the possible biological role of certain intracellular substrates. Another paper examines the role played by protein phosphorylation in the control of translation, or when possible, any additional regulatory mechanisms operating in other eukaryotic species. Biochemists, micro-biologists, bio-physicists, cellular researchers, and researchers involved in the study of cellular biology will find the collection very useful.
  • Pornography and Sexual Aggression

    • 1st Edition
    • Neil M. Malamuth
    • English
    Pornography and Sexual Aggression is an analysis of the various facets of pornography and sexual aggression and possible linkages between them. This 11-chapter work focuses on the causes of male aggression against women that may or may not occur within a sexual context, as well as on possible causes of sexual aggression that are not directly related to pornography. After a historical perspective on pornography research, this book goes on presenting the findings of a series of experimental studies that primarily focuses on the effects of violent or aggressive pornography fantasies, attitudes, beliefs, and aggressive behavior. The role of such factors as individual differences in aggressive inclinations, emotional states, and situational inhibitions in mediating the impact of aggressive pornography is also examined. These topics are followed by discussions of the ability of a theoretical model based on physiological arousal and emotional reactions, as well as the various individual difference variables that may affect reactions to pornography. Other chapters review the correlational data both within the United States and other areas of the world, along with some psychological and communicative factors that may cause sexual aggression. The concluding chapters describe the implications for legal change of some of the research, particularly on violent pornography. This book will prove useful to psychologists, psychiatrists, and behaviorists.