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  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 4
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 4 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation. Organized into six chapters, this volume begins with an overview of the activity of ornithine transcarbamylase that catalyzes the condensation of carbamyl phosphate with ornithine. This text then presents and discusses the in vitro data that are available on the molecular interactions that govern the expression of lactose (lac) operon. Other chapters consider the bovine liver, which has been characterized in terms of molecular and kinetic characteristics. This book discusses as well the de novo synthesis of saturated fatty acids, which is catalyzed by two enzyme systems. The final chapter deals with the factors leading to glycogenolysis as it occurs in mammalian skeletal muscle. This book is a valuable resource for biologists and biochemists.

  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 25
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation: Volume 25 is a collection of papers that deals with GTP, the central regulator of cellular anabolism, and the quantitative approach to metabolic control. , Other papers describe the inactivation and aldolases by limited proteolysis by lysosomal cathepsin M, the regulatory functions of proline, pyrroline-5-carboxyl... acid, as well as the characteristics of a hormonal regulation of amino acid transport. One paper suggests that GTP, possibly acting through high guanine nucleotide energy charge, acts to stimulate a wide variety of anabolic processes involved in cell growth or proliferation. Another paper proposes that lysosomes are responsible for the degradation of proteins and other macromolecules, and in regulating cytosolic enzymes. This action is due to the presence of selected proteinases (located on the outer lysosomal surface) that are active at neutral pH, and also which catalyze only limited proteolysis of cytosolic proteins. One paper describes the characteristics and hormonal regulation of a specific transport system for neutral amino acids, namely, the System A-mediated transport. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology.

  • Statistical Methods in Longitudinal Research

    Principles and Structuring Change
    • 1st Edition
    • Volume 1
    • Alexander von Eye
    • English
    These edited volumes present new statistical methods in a way that bridges the gap between theoretical and applied statistics. The volumes cover general problems and issues and more specific topics concerning the structuring of change, the analysis of time series, and the analysis of categorical longitudinal data. The book targets students of development and change in a variety of fields - psychology, sociology, anthropology, education, medicine, psychiatry, economics, behavioural sciences, developmental psychology, ecology, plant physiology, and biometry - with basic training in statistics and computing.

  • Centrifugation in Density Gradients

    • 1st Edition
    • C. A. Price
    • English
    Centrifugation in Density Gradients provides information pertinent to the fundamental aspects of density gradient centrifugation. This book discusses the benefits of density gradient centrifugation to membrane-bound particles. Organized into nine chapters, this book begins with an overview of the method of differential or fractional centrifugation. This text then explores the physical basis of density gradient centrifugation. Other chapters deal with the nuts and bolts of density gradient centrifugation, the construction and composition of gradients, the properties and operation of centrifuge systems, and certain arcane but highly useful procedures. This book discusses as well density gradient centrifugation in the analytical ultracentrifuge. The final chapter deals with a collection of protocols for separating particles ranging in size from whole cells to macromolecules. This book is intended to be suitable for readers who need to separate biological particles. Biologists, chemists, biochemists, cytologists, physiologists, scientists, and research workers will also find this book useful.

  • Current Topics in Cellular Regulation

    A Practice Manual
    • 1st Edition
    • Volume 28
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation: Volume 28 is a collection of papers that deals with enzyme-enzyme interactions, regulation of metabolic reaction pathways, the relevance of intracellular amino acid pool in the regulation of protein metabolism, and the production of superoxide by phagocytic leukocytes. Other papers discuss the regulation of adrenergic receptor function by phosphyrylation, a membrane-bound metallo-endopeptidas... (meprin), as well as the covalent modification as a mechanism of marking proteins for degradation. One paper notes that the transfer pathway involving enzyme-enzyme recognition is associated with molecular specificity features over those demanded by the molecular structural constraints of the individual enzyme sites. The Albery and Knowles principle, under certain conditions, shows that intermediary metabolites within a particular pathway exist in states of nearly equal free energy. One paper describes that the amino acid pool size and content are governed by the conditioning of intracellular proteins and the metabolic activity of the cell. The paper also suggests that intracellular pools do not regulate protein metabolism. The collection can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology or physiology.

  • Quantitative Planning and Control

    Essays in Honor of William Wager Cooper on the Occasion of His 65th Birthday
    • 1st Edition
    • Yuji Ijiri + 1 more
    • English
    Quantitative Planning and Control: Essays in Honor of William Wager Cooper on the Occasion of His 65th Birthday features a collection of papers prepared by students and associates of William Wager Cooper to honor him on the occasion of his sixty-fifth birthday. The book centers on the theme of Quantitative Planning and Control, the theme to which much of Professor Cooper's research effort has been devoted. The theme covers diverse fields of inquiry as reflected in the articles in this book, which are organized in four parts: (1) mathematical programming and decision models; (2) economic development and firm growth; (3) manpower planning and design; and (4) accounting and control. At the core of all of the articles in this book lies a belief that analytical approaches can help solve all managerial problems, a philosophy that is deeply rooted in Professor Cooper's thinking. This book demonstrates how this fundamental view on management can be reflected in dealing with problems in various fields of management. In particular, the book focuses on three main areas of application of this view, economic development, manpower planning, and accounting and control, along with the subject of developing tools that are necessary for solving managerial problems analytically.

  • Techniques in Protein Chemistry IV

    • 1st Edition
    • Ruth Hogue Angeletti
    • English
    Techniques in Protein Chemistry IV compiles papers presented at the Sixth Protein Society Symposium held in San Diego, California in 1992. This book discusses the mass spectrometry in protein sequence and structural investigations; site specific heterogeneity of N-linked oligosaccharides on recombinant human erythropoietin; and modification of thiophosphorylated proteins with extrinsic probes. The cysteine and tryptophan amino acid analysis of ABRF92-AAA; development of separation strategies for proteins by capillary electrophoresis; and peptide mapping of 2-D gel proteins by capillary HPLC are also elaborated. This text likewise covers the single syringe-pump solid-phase protein sequencer; hydrophobic contact density distribution functions; and application of chemical shift calculation to protein structure determination by NMR. This publication is valuable to biologists and students concerned with the developments in mass spectrometry of proteins.

  • Computational Vision

    • 1st Edition
    • Harry Wechsler
    • English
    The book is suitable for advanced courses in computer vision and image processing. In addition to providing an overall view of computational vision, it contains extensive material on topics that are not usually covered in computer vision texts (including parallel distributed processing and neural networks) and considers many real applications.

  • Introduction to Non-Euclidean Geometry

    • 1st Edition
    • EISENREICH
    • English
    An Introduction to Non-Euclidean Geometry covers some introductory topics related to non-Euclidian geometry, including hyperbolic and elliptic geometries. This book is organized into three parts encompassing eight chapters. The first part provides mathematical proofs of Euclid’s fifth postulate concerning the extent of a straight line and the theory of parallels. The second part describes some problems in hyperbolic geometry, such as cases of parallels with and without a common perpendicular. This part also deals with horocycles and triangle relations. The third part examines single and double elliptic geometries. This book will be of great value to mathematics, liberal arts, and philosophy major students.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 14
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 14 is a five-chapter text that covers other important aspects of lipid chemistry, including an enzyme controlling cholesterol biogenesis, fatty acid activation, and lipid synthesis. The first chapter concerns with the control of activity of ?-hydroxy-?-methylgl... coenzyme A reductase. The second chapter deals with the specificity, localization, and function of fatty acid activation. The third chapter describes the interaction between polyene antibiotics and sterols. This chapter specifically tackles some antibiotic activity to understand membrane function and in vivo hypolipidemic activity. The fourth chapter focuses on the lipids in plant cultures, while the fifth chapter looks into the methods of synthesis of acylglycerols and phosphoglycerides. This book will prove useful to lipid chemists, biochemists, and researchers.

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