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Elsevier

Academic Press

  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 10
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 10 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation. Organized into six chapters, this volume begins with an overview of the enzymes that exhibit half-of-the-sites activity. This text then examines the two different aspects of cyclic AMP-mediated systems. Other chapters consider the possible role of citrate synthase in the regulation of the citric acid cycle. This book discusses as well the regulation of the pentose phosphate pathway. The final chapter reviews the evidence for the occurrence of futile cycles at three control points in the metabolism of glucose, namely, at the level of glucose phosphorylation, at the interconversion of fructose mono- and biophosphates, and between pyruvate and phosphenol pyruvate. This book is a valuable resource for biochemists, biologists, and research workers.

  • Behavior of Nonhuman Primates

    Modern Research Trends
    • 1st Edition
    • Volume 4
    • Allan M. Schrier + 1 more
    • English
    Behavior of Nonhuman Primates: Modern Research Trends, Volume 4 provides information pertinent to research on behavior of nonhuman primates. This book presents a systematic investigation of memory processes in animals. Organized into four chapters, this volume begins with an overview of the implication of the obvious similarity of monkeys and humans in interproblem learning. This text then presents a series of investigations of the retention of object-discriminatio... learning by learning-set-experie... rhesus monkeys. Other chapters consider the capability of chimpanzees to handle at least rudimentary stages of certain higher mental functions. This book discusses as well the communicative behavior of animals, which is similar to the rest of animal behavior in that it is governed by general perceptual, motor, motivational, and associative laws. The final chapter deals with the main accomplishments of a program designed to teach language to a chimpanzee. This book is a valuable resource for students and research workers.

  • Molecular Mechanisms of Immunological Self-Recognition

    • 1st Edition
    • Frederick Alt + 1 more
    • English
    Molecular Mechanisms of Immunological Self-Recognition covers the understanding of immunological self-recognition. The introductory chapter of the book summarizes the dawn of the insight into immunological tolerance, and provides an overview of research on the underlying mechanisms. The book addresses the developments in the molecular mechanisms of B and T cell tolerance and describes the failure of tolerance in autoimmunity. The text concludes by furnishing orienting perspectives and highlighting new information presented. The novel findings characterized as impressive advances pertain to the areas of B cell development and the generation of molecular diversity; V gene usage, especially from transgenes, in positive and negative thymic selection; the handling of positive and negative signals by T and B cells; anergy in postthymic T cells; the design of peptide-based therapy for autoimmune diseases; and the design of therapy with the aid of monoclonal antibodies. Immunologists will find the text useful.

  • Developments in Statistics

    • 1st Edition
    • Volume 1
    • Paruchuri R. Krishnaiah
    • English
    Development in Statistics, Volume 1 is a collection of papers that deals with theory and application of parameter estimation in stochastic differential systems, the comparative aspects of the study of ordinary time series, and real multivariate distributions. Some papers discuss covariance analysis of nonstationary time series, nonparametric repeated significance tests, as well as discrete optimal factorial designs for statisticians and investigators of experiments. One paper cites an application of parameter estimation in stochastic differential systems in approximates of stability and control derivatives from flight test data. Another paper cites cases where procedures of ordinary time series (or point processes) have direct analogs in the study of point processes (or ordinary time series). One paper explains the applications of multivariate distributions in simultaneous tests on the equality of eigenvalues toward the covariance matrix, canonical correlation matrix, and a matrix associated with the multivariate analysis of variance. Another paper reviews two types of repeated significance tests, namely, the genuinely distribution-free tests based on a broad class of nonparametric statistics; and the asymptotically distribution-free tests based on a broad class of parametric statistics but having asymptotically nonparametric behavior. Both types can provide a unified solution to a broad class of problems. The collection can be valuable for mathematicians, students, and professors of calculus, statistics, or advanced mathematics.

  • Laminar Flow Forced Convection in Ducts

    A Source Book for Compact Heat Exchanger Analytical Data
    • 1st Edition
    • R. K. Shah + 1 more
    • Thomas F. Irvine + 1 more
    • English
    Laminar Flow Forced Convection in Ducts is a sourcebook for compact heat exchanger analytical data. This book describes the analytical solutions for laminar fluid flow and forced convection heat transfer in circular and noncircular pipes, including applicable differential equations and boundary conditions involving velocity and temperature problems of fluid flow. The book also discusses fluid flow—how much power is required to pump fluids through the heat exchanger, as well as the heat transfer—the determination of q" distribution, and the temperature of fluid and walls. The text also analyzes the coolant or heat transfer fluid flows in a nuclear power reactor composed of a bundle of circular section fuel rods located inside a round tube. R.A. Axford addresses fluid flow and heat transfers results for the rod bundle geometry in "Heat Transfer in Rod Bundles." The book also provides an overview and guidelines that can be used for the designer and the applied mathematician. This book is suitable for engineers working in electronics, aerospace, instrumentation, and biomechanics that use cooling or heating exchanges or solar collection systems.

  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 11
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 11 focuses on the biochemical mechanisms and key role of the liver in the homeostasis of blood glucose. This book begins with a discussion of glucokinase that is known to play a key role in glucose uptake by liver, followed by a broad overview of the mechanisms that control both glucose uptake by and release from the liver and enzymes involved in glycogen synthesis and breakdown. The classical enzyme models for allosteric regulatory mechanisms known as the biodegradative threonine deaminase are also elaborated. Other topics include the control of blood cholesterol levels, use of cultured mammalian cells, and studies of mutant cell lines. A model for protein turnover is likewise presented, including other mechanisms for the selective degradation of protein, selective uptake by lysosomes, and possible role of stabilizing factors. This publication concludes with an evaluation of complex regulatory mechanisms proposed for the regulation of photosynthetic carbon assimilation. This volume is recommended for biologists and researchers interested in advances in the general area of cellular regulation.

  • Current Topics in Bioenergetics

    Volume 13
    • 1st Edition
    • C. P. Lee
    • English
    Current Topics in Bioenergetics, Volume 13 presents the biophysical and biochemical approaches that are valuable in some systems and that may be readily be applied to others. This book discusses the function and structure relationship of energy-transducing membranes that has played an essential role in the progress and development in the field of bioenergetics. Organized into six chapters, this volume begins with an overview of the bioenergetics processes that require a molecular description of the structure and reaction mechanisms of the individual energy-transducing catalysts. This text then provides an understanding to the methodology for initiation of an electron paramagnetic resonance (EPR) investigation in this field of research. This book discusses as well the developments in spin label EPR techniques. The final chapter deals with immunological techniques that are used for studying the biochemistry and molecular biology of membrane proteins. This book is a valuable resource for physiologists, biologists, and biochemists.

  • Analytical Applications of Immobilized Enzymes and Cells

    Applied Biochemistry and Bioengineering, Vol. 3
    • 1st Edition
    • Volume 3
    • Lemuel B. Wingard + 2 more
    • English
    Analytical Applications of Immobilized Enzymes and Cells, Volume 3 presents a survey of the interdisciplinary interactions, developments, and trends on research in immobilized enzymes and cells. This volume is comprised of eight chapters. Chapters 1 to 4 are devoted to the description of methodologies and instrumentations which are used in routine analysis. Among those described are enzyme tubes, enzyme thermistors, and enzymic or microbial electrodes. Chapter 4 provides a theoretical analysis of electrode design. Subsequent chapters focus on solid-phase enzyme immunoassays and on techniques for in vivo monitoring of metabolites; economic evaluation of the use of high-purity enzymes in analysis; and an assessment of the significance of microprocessors and computer science in enzyme based analysis. Chemists and chemical engineers will find the book very useful.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 1
    • Norman J. Lass
    • English
    Speech and Language: Volume 1, Advances in Basic Research and Practice is a compendium of papers that discusses the processes and pathologies of, as well as applies theories and clinical issues to, speech and language. Some papers discuss perception of speech in early infancy, the problems faced by speech clinicians, and the anatomy of the perioral motor system. Based on data compiled on the infant's perception of speech sounds, one paper notes that human infants discriminate depending on fine temporal and frequency changes in a complex auditory array. Infants also show perceptual constraints while listening to speech characterized as adult- like; they are also predisposed to perceive certain speech-sound categories such as vowel and fricative categories. One paper examines the suggestion of Kent (1976) that "acoustic characteristics of children's speech...hold the promise of sensitive methods for the study of speech maturation and developmental disorders." This investigation involves the following: the recent attempts at multidimensional analyses of speech and perception; a measure of perceptual contrast; and results of feature comparison efforts. The compendium is well suited for linguists, ethnologists, psychologists, and researchers whose works involve linguistics, language learning, communications, and syntax.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 9
    • Norman J. Lass
    • English
    Speech and Language: Advances in Basic Research and Practice, Volume 9 is a collection of contributions that discuss a broad range of topics on speech and language processes and pathologies. This volume contains seven contributions covering a wide array of topics on speech and language. It covers topics on speech development and production in normal and hearing-impaired speakers; integrated speech and language instruction for the hearing-impaired adolescent; and laryngectomee rehabilitation. Also discussed are subjects on sensory and motor changes during development and aging; the phonetic structure of errors in the perception of fluent speech; and the multiple meanings of phoneme and their confusions. Linguists, speech pathologists, and researchers on language development will find the book very insightful and informative.

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