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Academic Press

  • Epilepsy

    Its Phenomena in Man
    • 1st Edition
    • Mary A. B. Brazier
    • English
    Epilepsy: Its Phenomena in Man is a 16-chapter text that covers the wide field of the phenomena of epilepsy in man. This book emerged from the manuscripts presented by the scientific program of an alumni reunion of the Brain Research Institute of the University of California, Los Angeles. The introductory chapters review the role of electricity in the exploration and elucidation of the epileptic seizure, as well as the role of synaptic organization of the cerebral cortex in epilepsy. The succeeding chapters deal with the neuroglial impairment hypothesis, the particular forms of experimental epilepsy in man, and their corresponding surgical treatment. These topics are followed by discussions of the problem of synchronization in the spread of epileptic discharges leading to seizures and the behavioral correlations of generalized spike-wave discharge in the electroencephalogram... Other chapters explore the common anatomy of psychomotor epilepsy and schizophrenia; time of occurrence of seizures; the clinical ictal patterns and electrographic data in partial seizure cases; and the problems of analysis and interpretation of electrocerebral signals in human epilepsy. The concluding chapters consider the developments in direct recordings from epileptogenic regions in the surgical treatment of partial epilepsies. These chapters also examine the golgi survey concerning hippocampal pathology in temporal lobe epilepsy and the structural substrates of seizure foci. This book will prove useful to neuroscientists and the workers in biomedical fields critical for the understanding of epileptogenesis.
  • Total Pressure Measurements in Vacuum Technology

    • 1st Edition
    • A. Berman
    • English
    Total Pressure Measurements in Vacuum Technology focuses on the measurement of low total pressure in hostile environments or in the presence of magnetic fields. This book emphasizes the general processes and problems involved in measurement techniques and physical principles on which vacuum gauges operate, rather than on the detailed description of the gauges. The design and techniques involved in the use of special instruments that determine “pressure” or gas density, such as pressure converters or radioactive gauges, are also described. This publication is mainly intended for graduate students and research scientists who have a good general background in physics and engineering.
  • Clinical Immunobiology

    • 1st Edition
    • Volume 2
    • Fritz H. Bach + 1 more
    • English
    Clinical Immunobiology, Volume 2 covers the advances in the field being made to apply bone marrow transplantation to the treatment of several diseases. This volume is divided into 11 chapters and begins with surveys of the clinical considerations of bone marrow transplantation. Considerable chapters are devoted to the application of this transplantation to the treatment of various diseases, including aplastic anemia, aregenerative pancytopenia, leukemia, uniformly fatal severe combined immunodeficiency diseases, and Wiskott-Aldrich syndrome. Other chapters examine the cellular engineering in the form of bone marrow and thymus transplantation. The remaining chapters consider the effects of exposure to excessive amounts of radiation or cytotoxic chemicals, as well as the hematopoietic failure based on malfunction of the complex process of normal hematological development and maintenance. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.
  • Current Topics in Bioenergetics

    Volume 6
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 6 provides information pertinent to the phenomenon of energy transduction. This book covers a wide variety of topics, including photosynthesis, muscle contraction, transport across membranes, and oxidative phosphorylation. Organized into six chapters, this volume begins with an overview of the solute transport functions of membrane vesicles from kidney and intestine. This text then examines the specialized calcium transport system of mitochondria from both mechanistic and biological viewpoints. Other chapters consider the energy-transducing mechanisms in bacteria and chromoplast from the standpoint of mechanism. This book discusses as well ionophores and channel formers as powerful tools in the study of membrane function. The final chapter deals with the metabolic link between fundamental cell physiological events, such as hormonal perturbation of metabolism and cell development, on the one hand, and an altered ability of mitochondria to transport Ca2+, on the other. This book is a valuable resource for bioenergeticists, biochemists, biologists, and microbiologists.
  • Developments in Statistics

    • 1st Edition
    • Volume 3
    • Paruchuri R. Krishnaiah
    • English
    Development in Statistics, Volume 3 is a collection of papers that deals with asymptotic expansions in parametric statistical theory, orthogonal models for contingency tables, statistical concepts in economic analysis, and an exposition of path analysis. One paper presents an inference model based on a sample of independent identically distributed observations to arrive at a general statistical theory founded on asymptotic methods. Another paper discusses the applicability of statistical concepts to economics and related areas, with emphasis on not-so-obvious applications (known as utility and expected loss). The paper explains information theory concepts for the measurement of income inequality, intergenerational occupational mobility, as well as to first- and second-order moments of univariate and bivariate distributions (such as measurements applied to the cost of living and of real income). One paper notes that the starting point in path analysis is a linear predictor (in the least-squares sense) for one random variable in terms of a number of others. The paper adds that the work of Koopmans and Hood (1953) on econometrics is part of the starting point. Statisticians, economists, mathematicians, students, and professors of calculus or advanced mathematics will surely appreciate the collection.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 4
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 4 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation. Organized into six chapters, this volume begins with an overview of the activity of ornithine transcarbamylase that catalyzes the condensation of carbamyl phosphate with ornithine. This text then presents and discusses the in vitro data that are available on the molecular interactions that govern the expression of lactose (lac) operon. Other chapters consider the bovine liver, which has been characterized in terms of molecular and kinetic characteristics. This book discusses as well the de novo synthesis of saturated fatty acids, which is catalyzed by two enzyme systems. The final chapter deals with the factors leading to glycogenolysis as it occurs in mammalian skeletal muscle. This book is a valuable resource for biologists and biochemists.
  • Visual Information Processing

    Proceedings of the Eighth Annual Carnegie Symposium on Cognition, Held at the Carnegie-Mellon University, Pittsburgh, Pennsylvania, May 19, 1972
    • 1st Edition
    • William G. Chase
    • English
    Visual Information Processing documents the Proceedings of the Eighth Annual Carnegie Symposium on Cognition, held at the Carnegie-Mellon University, Pittsburgh, Pennsylvania on May 19, 1972. This book compiles papers on the results from ongoing, programmatic research projects that aim to develop information processing models of cognition. The role of visual processes in cognition and language comprehension and explicit computer simulation of the memory-scanning task are discussed in detail. Other topics include the chronometrie studies of the rotation of mental images; function of visual imagery in elementary mathematics; and semantic prerequisites for comprehension. The production system for counting, subitizing, and adding; visual processes in linguistic comprehension; and models of control structures are also deliberated. This publication is a good source for students and researchers interested in images.
  • Current Topics in Bioenergetics

    Volume 9
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 9 presents the theoretical, thermodynamic perspective of energy transducing reactions. This book provides a detailed kinetic analysis of a specific aspect of an ion pump. Organized into seven chapters, this volume begins with an overview of the quantitative relations between measurable parameters of energy-transducing systems. This text then examines the probes for intracellular pH determination, which stimulate the development of additional methods and their application in pathology and pharmacology. Other chapters consider studies with isolated proteins or protein complexes derived from the membranes. This book discusses as well the chemistry of photosynthesis and oxidative phosphorylation. The final chapter deals with the advances in the use of photo affinity labeling in the study of the structure of ligand sites on proteins, which became possible only in conjunction with the development of methods for the isolation of peptides and their sequence determination. This book is a valuable resource for biologists and biochemists.
  • Advances in Lipid Research

    • 1st Edition
    • Volume 10
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 10 is a six-chapter text that is devoted to several special areas of lipid research, including significant progress in established areas of interest in the field. The introductory chapter surveys the application of electron microscopic techniques to the analysis of plasma lipoproteins. The subsequent chapter deals with the possible modification of reticuloendothelial functions by lipids and the role of lipids in cellular, humoral, and immune responses. These topics are followed by discussions of the microsomal enzymes of sterol biosynthesis and the enzymatic synthesis and degradation of glycerol lipids, which contain ether bonds. The remaining chapters focus on lipid neurochemistry. These chapters specifically examine particular brain lipids, such as fatty acids, phospholipids, sphingolipids, galatosyl lipids, and sterols. A discussion of lipids of the entire nervous system and their variation with age is also included. This book will prove useful to lipids chemists, biochemists, and organic chemists.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 32
    • Earl R. Stadtman + 2 more
    • English
    Current Topics in Cellular Regulation: Volume 32 is a collection of papers that discusses the role of GTP-binding proteins in signal transduction, the activation of cholera toxin by ADP-ribosylation factors, and the signal transduction by the colony-stimulating factor-1 receptor. Other papers explain the secretory granule, the mechanism of stimulus-secretion coupling, calcium pumps in the plasma and intracellular membranes, as well as the protein phosphorylation in translational control. One paper proposes a linkage between the multimeric structures and cytoskeletal elements to bridge the signal transducing systems and the cytoskeletal network. Another paper describes the signaling mechanisms utilized by CSF-1R, the similarities, and differences when compared to other receptor tyrosine kinases (RTKs). The paper explains in detail the mechanism of ligand-induced kinase activation, and also the possible biological role of certain intracellular substrates. Another paper examines the role played by protein phosphorylation in the control of translation, or when possible, any additional regulatory mechanisms operating in other eukaryotic species. Biochemists, micro-biologists, bio-physicists, cellular researchers, and researchers involved in the study of cellular biology will find the collection very useful.