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Elsevier

Academic Press

  • Sparse Matrix Technology

    • 1st Edition
    • Sergio Pissanetzky
    • English
    Sparse Matrix Technology presents the methods, concepts, ideas, and applications of sparse matrix technology. The text provides the fundamental methods, procedures, techniques, and applications of sparse matrix technology in software development. The book covers topics on storage schemes and computational techniques needed for sparse matrix technology; sparse matrix methods and algorithms for the direct solution of linear equations; and algorithms for different purposes connected with sparse matrix technology. Engineers, programmers, analysts, teachers, and students in the computer sciences will find the book interesting.

  • Recent Progress of Life Science Technology in Japan

    • 1st Edition
    • Yoji Ikawa + 1 more
    • English
    Recent Progress of Life Science Technology in Japan discusses developments in cancer research technologies in Japan. In June 1983 an intra-cabinet panel of the Japanese Government drafted a 10-year strategy for cancer control, recognizing the importance of this field of research. A scientific research group was organized to comprise two sections—the first concerning the development and evaluation of DNA technologies, and the second on protein-related technologies. In the promotion of fundamental cancer research, the development and refinement of basic technologies for each component of the ""triangle of bio-sciences""—DNA, protein, and antibody—are essential, particularly in the elucidation of tumor-inducing and tumor-suppressing genes, tumor-specific antigens, and so forth. Part I of the book details the achievements of the first group in developing automated instrumentations for DNA sequencing. The second scientific research group worked on three major subareas: (1) gene transfer and expression technologies; (2) technologies for extraction, purification, and structural analysis of cancer-related proteins; and (3) technologies for analysis and synthesis of saccharide chains. Reports from these areas are respectively grouped in Part II, Part III, and Part IV of this monograph.

  • Quick Answers to Quantitative Problems

    A Pocket Primer
    • 1st Edition
    • G. William Page + 1 more
    • English
    No matter the field, professionals need to respond quickly to quantitative problems as they arise and to develop a quick understanding of what the data mean. Whether you are an aide to a city council member trying to decipher the true meaning of a citizen opinion poll, a private consultant to the health department estimating the number of pregnant teenagers in a neighborhood, or the executive director of a small agency striving to present your budget facts precisely and clearly, the techniques presented here are helpful to you and your work.

  • Psychoneuroimmunology

    • 1st Edition
    • Robert Ader
    • English
    Psychoneuroimmunolog... Second Edition presents reports on the relationship between the nervous and immune systems. The book is divided into four sections. The first section details the role of neural structures and neurotransmitter signals in communication with the immune system. It documents the extensive neural connections with organs of the immune system; the dynamics of noradrenergic sympathetic innervation of spleen and thymus; and the evidence for immune signaling of the CNS. Part II elaborates the role of hormones in the modulation of immune functions; the basis for bidirectional communication between the neuroendocrine and immune systems; and the potential physiological implications of these neuroendocrine-immun... system interactions. The third part addresses behavioral influences on immune response; the effects of conditioning, stress and social interactions in modulating immune responses; and the behavioral consequences of experimentally altered or genetically determined immunologic states. The final section presents the effects of psychosocial factors on immune responses and the potential impact of behavioral interventions in modulating immunity in healthy human subjects and in patients with AIDS. Neuroscientists, endocrinologists, and immunologists will find the book interesting.

  • Multiple Equilibria in Proteins

    • 1st Edition
    • Jacinto Steinhardt + 1 more
    • Bernard Horecker + 2 more
    • English
    Multiple Equilibria in Proteins covers the multiple interactions between small ions and molecules and a protein molecule. The book also deals with the physicochemical mechanisms of this interaction and the information about protein structure and the forces stabilizing that structure. The text discusses the mathematical description of complex formation, the thermodynamic analysis of binding data, and various theoretical models which can be used to describe the phenomena of small molecule-macromolecu... interactions. The measurement of complex formation; the binding of neutral molecules; and hydrogen-ion equilibria are also considered. The book further tackles metal-ion binding; the binding of organic ions by proteins; as well as protein-protein interaction. Chemists and biochemists will find the book useful.

  • Clinical Immunobiology

    • 1st Edition
    • Volume 4
    • Fritz H. Bach + 1 more
    • English
    Clinical Immunobiology, Volume 4 is a 13-chapter text that covers the advances in understanding of the concepts and practical applications of lymphoid subpopulations and the major histocompatibility complex (MHC). The first chapter presents an overview of the problems of various subpopulations of cells involved in the immune system. The succeeding chapters describe the techniques used for cell classification, either by their cell surface phenotype or by their responsiveness to a series of different stimuli. These chapters include surveys of the methods of detection of complement receptors and expression of these receptors on the surface of both normal and leukemic human lymphocytes. A discussion of the evidence that different T-lymphocyte populations differentially express receptor for IgG and IgM is also provided. Other chapters describe the relationship of MHC to serology of cell surface antigens and reactivity in the mixed leukocyte culture test. This work also explores the methods that employ the so-called "proliferative and cytotoxic responses". The remaining chapters look into the association between HLA antigens and a variety of different diseases. These chapters also discuss other genetic markers in the HLA linkage group. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.

  • Mechanisms of Eukaryotic DNA Recombination

    • 1st Edition
    • Max E Gottesman + 1 more
    • English
    Mechanisms of Eukaryotic DNA Recombination is a collection of papers that discusses advances in eukaryotic genetic recombination. Papers address issues in eukaryotic genetic recombination, particularly DNA integration in mammalian genomes, genetic recombination in Drosophila or Caenorhabditis; the manipulation of the mouse genome; genome organization; and genetic recombination in protozoa. One paper discusses chromatid interactions during intrachromosomal recombination in mammalian cells, namely, intrachromatid and sister chromatid. Another paper analyzes the implication for chromosomal recombination and gene targeting; results on extrachromosomal recombination show that circles are inefficient substrates for recombination even if only one of two substrates in an intermolecular reaction is circular. One author discusses the genetics and molecular biology of recombination, citing the work of Watson and Crick, stating that crossing-over occurs between genes (not within them). He also explains that the formation and resolution of recombination intermediaries depend on enzyme or other proteins. This book will prove invaluable to cellular biologists, microbiologists, and researchers engaged in genetics and general biology.

  • Transfer Factor

    Basic Properties and Clinical Applications
    • 1st Edition
    • Michael S. Ascher + 2 more
    • English
    Transfer Factor: Basic Properties and Clinical Applications covers papers about transfer factor. The book presents papers on the in vitro studies of transfer factor; the characterization of transfer factor; and the animal models of transfer factor. The text also includes articles on the use of transfer factor in infectious and neoplastic diseases and transfer factor therapy. Examples of papers on transfer factor therapy include the role of transfer factor in the treatment of lymphoma cutis in Wiskott-Aldrich syndrome, transfer factor immunotherapy of rheumatoid arthritis, and transfer factor therapy in a patient with an isolated T-cell deficiency. Immunologists, pathologists, oncologists, microbiologists and people involved in the study of infectious diseases will find the book invaluable.

  • Fuzzy Sets and Their Applications to Cognitive and Decision Processes

    Proceedings of the U.S.–Japan Seminar on Fuzzy Sets and Their Applications, Held at the University of California, Berkeley, California, July 1-4, 1974
    • 1st Edition
    • Lotfi A. Zadeh + 2 more
    • English
    Fuzzy Sets and Their Applications to Cognitive and Decision Processes contains the proceedings of the U.S.-Japan Seminar on Fuzzy Sets and Their Applications, held at the University of California in Berkeley, California, on July 1-4, 1974. The seminar provided a forum for discussing a broad spectrum of topics related to the theory of fuzzy sets, ranging from its mathematical aspects to applications in human cognition, communication, decision making, and engineering systems analysis. Comprised of 19 chapters, this book begins with an introduction to the calculus of fuzzy restrictions, followed by a discussion on fuzzy programs and their execution. Subsequent chapters focus on fuzzy relations, fuzzy graphs, and their applications to clustering analysis; risk and decision making in a fuzzy environment; fractionally fuzzy grammars and their application to pattern recognition; and applications of fuzzy sets in psychology. An approach to pattern recognition and associative memories using fuzzy logic is also described. This monograph will be of interest to students and practitioners in the fields of computer science, engineering, psychology, and applied mathematics.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 18
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 18 is a seven-chapter text that brings together significant research studies on atherosclerosis. The opening chapter describes the pathological techniques in atherosclerosis research. The succeeding chapters deal with the influence of lipid-lowering drugs on bile acid metabolism and the cholesterol metabolism in ovarian tissue. Other chapters examine the principal role of sulfolipids and the influence of dietary linoleic acids on blood pressure regulation in rats. The closing chapters review the influence of nonnutritive fiber on lipid metabolism and the influence of fiber on lipid-associated diseases. These chapters also consider the techniques for polar lipid analysis. This book will be of great value to lipid chemists, biochemists, and researchers.

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