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Elsevier

Books in Neuroscience

Elsevier's Neuroscience collection empowers educators, researchers, and students with actionable knowledge to drive collaborative research and advancements in the field. Content covers the nervous system's intricate workings, covering branches like Affective, Behavioral, and Cognitive neuroscience to investigate the neural basis of emotions, behavior, and cognitive functions. Spanning from Molecular and Cellular Neuroscience to Developmental Neuroscience, content provides insights into brain function in health and disease.

  • Quantitative and Qualitative Microscopy

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 3: Quantitative and Qualitative Microscopy is a collection of papers that deals with microscopic techniques in statistical measures. This volume describes microscopy using sophisticated stains and dyes to advance observation of tests and experiments. Section I describes autoradiography including micro chemical methods, high-resolution autoradiography, and single- or double-label quantitative autoradiography for use in imaging of brain activity patterns or determining cerebral physiology. Section II discusses the quantification of structures through statistical and computational methods including dynamic video imaging technology. Section III explains the use of tracers, toxins, or dyes in tracing neuronal connections. One paper addresses the use of small injections of axonally transported fluorescent tracers. Section IV explains staining technology such as using the silver impregnation method for frozen sections of human nervous tissue that are gathered from tissues preserved in formalin. Section V addresses freezing techniques and those using freeze-fracture methods in neurobiology. The text also discusses cryoprotection and other freezing methods to control ice crystals found in fixed or unfixed brain tissues. Section VI presents the combined and high-resolution methods in polarization microscopy and microscopic investigations. Cellular biologists, micro-chemists, and scientific researchers in the field of micro- and cellular biology will appreciate this book.

  • Neuropeptide Technology

    Synthesis, Assay, Purification, and Processing
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 6: Neuropeptide Technology: Synthesis, Assay, Purification, and Processing describes procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into four sections— chemical synthesis and biosynthesis; measurement of neuropeptides; purification and characterization; and neuropeptide degrading and processing enzymes. In these sections, this book specifically discusses the synthesis of peptide substrates for protein kinase C; synthesis of glycosyl neuropeptides; and ultrastructural localization of peptides. The measurement of neurokinin B by radioimmunoassay; purification and characterization of neuroendocrine peptides from rat brain; and preparation of glia maturation factor ß are also elaborated. This text likewise covers the assays for arginine/lysine carboxypeptidases and enzymes that metabolize atrial natriuretic peptide. This publication is beneficial to neuroscientists and students researching on the synthesis, assay, purification, and processing of neuropeptides.

  • Biophysical Aspects of Cerebral Circulation

    • 1st Edition
    • Yu. E. Moskalenko + 2 more
    • English
    Biophysical Aspects of Cerebral Circulation provides a comprehensive review of the cerebral circulatory system. This book consists of four chapters. Chapter 1 is devoted to methodology attempts to explain the special features of a biophysical approach. The biophysical principles of the most commonly used modem methods such as the clearance method and rheoencephalography are described in detail. The second and third chapters examine all the biophysical aspects of the cerebral circulatory system as a functional unit and deal with some principles of its regulation. The results of systems analysis using mathematical modeling are presented in broad outline. Chapter 4 deals with processes related to the regional cerebral circulation. Such investigations focus mainly on the relationship between periodically fluctuating factors affecting limited areas of brain tissue. This text is beneficial to medical students and individuals researching on cerebral circulation.

  • Receptors

    Model Systems and Specific Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.

  • Clinical Methods of Neuro-Ophthalmologic Examination

    • 1st Edition
    • Alfred Kestenbaum
    • English
    Clinical Methods of Neuro-Ophthalmologic Examination presents the clinical methods of ophthalmologic examination that may be helpful in neurologic differential diagnosis. Neuro-ophthalmologic examination has developed in two directions: the more precise methods and the unrefined yet fairly exact methods, such as diagnostic measurement by means of a simple ruler. This book is based on lectures delivered by the author to neurologists and ophthalmologists. This book is composed of 13 chapters and begins with a presentation of anatomic details that are important for the understanding of the various signs and symptoms. The next chapters examine the development of simple perimetry into quantitative perimetry and angio-scotometry, as well as the pathology of the optic nerve. Considerable chapters are devoted to intensive discussions on group of diseases that affect in a parallel way the central nervous system and the eye, such as chiasmal and retrochiasmal lesions, nystagmus, symmetrical eye movement disturbance, palpebral fissure, hemicrania. The final chapter outlines a routine neuro-ophthalmologic... examination. This book is directed toward neurologists and ophthalmologists.

  • Cerebral Palsy

    A Clinical and Neuropathological Study
    • 1st Edition
    • Erna Christensen + 1 more
    • English
    Cerebral Palsy: A Clinical and Neuropathological Study is an account of a detailed study in which obstetrical, neonatal and neurological investigations on a large group of patients are presented with full neuropathological data found at subsequent necropsy. The book discusses the general autopsy findings and neuropathological techniques; as well as neuropathological findings in the different clinical entities. The text also describes the neuropathological findings and classification; progressive encephalopathies; and epilepsy. Neurologists will find the book invaluable.

  • The Release of Catecholamines from Adrenergic Neurons

    • 1st Edition
    • David M. Paton
    • English
    The Release of Catecholamines from Adrenergic Neurons covers the advances in understanding the mechanism of catecholamine release and other neurotransmitters from adrenergic neurons. This book is organized into four sections encompassing 18 chapters. The opening section surveys biochemical studies of the mechanism and regulation of nerve stimulation. This section examines the role of calcium, prostaglandins, and presynaptic adrenoceptors and muscarine receptors in catecholamine release. The next section describes the modification of catecholamine release by several drugs, including adrenergic neuron blocking agents, narcotic analgesics, opioid peptides, lysergic acid diethylamide, anesthetics, alcohols, and adenosine and adenine nucleotides. These topics are followed by discussions of catecholamine release induced by cations and other drugs, such as nicotinic agonists, calcium ionophores, veratridine, scorption venom, and phenethylamines. The final section deals with the biochemical assessment of peripheral adrenergic activity and the clinical pharmacology of adrenergic neuron blocking agents. This book is intended for pharmacologists, neurologists, researchers, and advanced students.

  • Neurogenic Heart Lesions

    • 1st Edition
    • I. S. Zavodskaya + 2 more
    • English
    Neurogenic Heart Lesions reviews the main publications concerned with the problem of neurogenic lesions of the heart. The book describes the methods for producing experimental neurogenic lesions, as well as the pharmacological analysis of the participation of the sympathetic nervous system and its transmitters in the development of neurogenic lesions of the myocardium. The text also discusses the changes in energy metabolism and in functional conditions of the myocardium caused by neurogenic lesions; and the pharmacoprophylaxis and pharmacotherapy of the biochemical changes produced by neurogenic lesions of the myocardium. Pharmacologists, pathologists, and other clinicians and physicians concerned with the new achievements in the field of cardiology will find the book invaluable.

  • Diagnostic Reference Index of Clinical Neurology

    • 2nd Edition
    • Pasquale F. Finelli
    • English
    Diagnostic Reference Index of Clinical Neurology aims to give the busy clinician a fast, easy-to-use guide to the core neurological literature published from 1980 to 1986. This book is divided into two sections, key words and references. The keywords section consists of neuroscience terms and each main entry is followed by reference citation numbers and corresponding references. This index, unlike the usual computerized systems for literature retrieval, is structured around clinical problems and uses the approach and terminology of a practicing neurologist. The contents were sources from the full text of articles that were published in critical core of fourteen major international English-language journals in medicine and neurology. This book will be of interest to neurology students and to practicing clinical neurologists.

  • Receptors in the Human Nervous System

    • 1st Edition
    • F. A. O. Mendelsohn + 1 more
    • English
    Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.

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