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Books in Life sciences

  • Cryo-EM Methods and Management

    • 1st Edition
    • Edward T. Eng + 2 more
    • English
    Cryo-EM Methods and Management provides a detailed introduction to the latest advances of cryo-EM, from technical innovations to the logistical challenges of maintaining a modern cryo-EM facility. The book consists of four parts, beginning with an overview of cryo-EM. It then moves on to discuss Cryo-EM workflows, with chapters focusing on sample handling and preparation, data collection and hardware, and data procession and visualization. The third part centers on aspects of cryo-EM infrastructure and community building, considering facility set-up and management, monitoring facility performance, instrumentation monitoring , data sharing and standards, and training and development standards. The book then closes with a section looking towards future prospects for cryo-EM. This is an ideal reference for cryo-EM facility and lab managers, providing guidance to the often-overlooked aspect of facility building and management. Additionally researchers working with cryo-EM across molecular biology, structural biology, cell biology and biochemistry will benefit from this book.
  • Humanizing Artificial Touch

    Skin, Sensing, and Structures
    • 1st Edition
    • John-John Cabibihan
    • English
    Humanizing Artificial Touch: Skin, Sensing, and Structures contains recent advances in artificial skin modelling and robotic tactile sensing technologies, integrating these in the structure of an artificial hand mimicking its important features. This book will give special treatment to the relationship between the artificial skin material and embedded tactile sensors, describing how artificial skin and embedded sensors can be designed and constructed using 3D printing technologies with case examples on how these were created for amputees achieve a more a natural and rich human-robot tactile interaction.This book is oriented towards students, researchers, and clinical practitioners who are working in the design and construction of artificial hands for prosthetics and social robotics.
  • Coronary Physiology in the Cardiac Cath Lab

    • 1st Edition
    • William F. Fearon
    • English
    Coronary Physiology in the Cardiac Cath Lab provides the foundational knowledge required to understand the concepts behind a variety of coronary physiologic assessments performed and required to apply them effectively when evaluating cardiac patients. Written to bring a practical and evidence-based approach, this book is a valuable resource for interventional and general cardiologists, cardiology researchers, physicians, cardiac catheterization laboratory staff, and anyone interested in understanding the theory and current practice surrounding assessing coronary physiology in the cardiac cath lab.Over the past decade, there has been an explosion of data validating the importance of assessing coronary physiology at the time of coronary angiography. This has led to the development of numerous new techniques and metrics for performing these assessments and also resulted in the inclusion of these indices into practice guidelines.
  • Conceptual Breakthroughs in Comparative Animal Physiology

    • 1st Edition
    • James Hicks + 1 more
    • English
    Conceptual Breakthroughs in Comparative Animal Physiology tells a story of innate human curiosity about the natural world, and a deeply creative discipline, shaped by varied environments, unusual organisms, elegant experiments, and the persistent effort to understand how animals work and why they work the way they do; and along the way discovery of “adaptations and mechanisms of the most surprising character”.Written by two leading experts in the field, each chapter reflects on the origins of ideas and the approach of turning natural diversity into experimental design. From deserts to oceans, from the anoxia-tolerant animals to endothermic insects, from deep-diving mammals to the integration of ‘omics’; each chapter follows the discoveries and people who were compelled to modify their view of "what life can do". The chapters also highlight the long-term influence of key conceptual breakthroughs, demonstrating how insights from comparative physiology have shaped not only the field itself but also, ecology, evolution, and engineering. As scientists strive to understand the complexity of, the book underscores the inherit integrative nature of, revealing a process that strives to connects genes to organisms and organisms to environments, and providing a framework understanding the diversity of life. This is an essential resource for undergraduates, graduate students and researchers interested in physiology with its comprehensive synopsis on the field’s foundational history and significant advances.
  • The AI Frontier in Molecular Modelling and Drug Designing

    • 1st Edition
    • Manish Kumar Gupta + 2 more
    • English
    The AI Frontier in Molecular Modelling and Drug Designing aims to provide a comprehensive guide on the application of AI concepts in drug designing, discovery, and molecular modeling. The book delves into machine and deep learning techniques that predict structural properties of molecules, identify druggable pockets, and assess physicochemical properties of targets. Sections explore current and potential computational resources to tackle complex biological challenges. Each chapter is enriched with relevant examples, text boxes, and case studies that illustrate the practical application of AI techniques, their outcomes, and the challenges faced during implementation.This resource is tailored for researchers, students, and professionals in both academia and industry, providing them with the latest methodologies, advancements in technology, and practical insights into AI-driven drug research, structural biology, computational biology, and translational science.
  • Molecular Insights into Proteinopathies

    Increased Scope from Neurodegeneration to other Pathologies of the Brain
    • 1st Edition
    • Eva Žerovnik + 1 more
    • English
    Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.
  • Non-chicken Poultry Production

    • 1st Edition
    • Caven Mguvane Mnisi + 2 more
    • English
    Non-chicken Poultry Production focuses on the modern production of non-chicken poultry birds as alternatives to diversify animal protein options and complement conventional chicken production. The book offers a general review of the sustainable production of non-chicken birds followed by nutritional considerations for each bird of interest. Various strategies to improve the nutrition, welfare, and health of the birds are covered, with an emphasis on long-term economic viability and sustainability. It ultimately examines the future outlook for establishing long-term, sustainable production systems, helping aid academic and industry researchers meet the demand of growing populations and contributing to global food security.Demand for chicken and eggs has surged with population growth, rising income levels, and urbanization. Meeting the demand has proved a challenge for farmers and other stakeholders.
  • Saving Songbirds

    Imperatives of Conservation in a Changing World
    • 1st Edition
    • Stefania Casagrande + 2 more
    • English
    Saving Songbirds: Imperatives of Conservation in a Changing World is a timely work that delves into the complexities of songbird conservation. As global ecosystems face unprecedented challenges, the symphony of birdsong – a vital indicator of ecological health – is under threat. This book, bringing together eminent voices from various corners of the globe, paints a holistic picture of these threats, their impacts on songbird evolution, and possible solutions. Edited by a leading team of expert ornithologists, this book introduces the import and global status of songbirds before delving into the myriad anthropogenic and global change-induced threats to songbird populations. Central chapters discuss the physiological and behavioral adaptations of songbirds to these modern stressors. The book concludes with a look to the future of songbird populations and the landscape of management and conservation opportunities to protect these critical species. Saving Songbirds: Imperatives of Conservation in a Changing World bridges gaps in current knowledge and introduces fresh perspectives on songbird conservation and scientific research, offers actionable advice and strategies for conservationists, policymakers, and scientists and represents a unique resource for university courses, ranging from ecology to environmental policy. Its structured layout and comprehensive scope make it suitable for diverse academic levels, from undergraduate to postgraduate studies.
  • Inflammation in Tumorigenesis and Cancer Treatment

    From Molecular Mechanisms to Personalized Therapeutic Strategies
    • 1st Edition
    • Chunxiang Zhang + 1 more
    • English
    Inflammation in Tumorigenesis and Cancer Treatment: From Molecular Mechanisms to Personalized Therapeutic Strategies explores the pivotal role of inflammation in cancer. It uncovers the molecular dialogue between inflammatory factors and tumor cells, illuminating pathways that drive oncogenesis and metastasis. Highlighting the rapid pace of discovery, the book bridges the gap by translating complex data into actionable clinical strategies, catering to students and professionals and addressing personalized medicine. Early chapters focus on the fundamental concepts of inflammation in cancer and recent advances in research, while also covering the impact of inflammatory mediators on signaling pathways and oncogenesis.Other sections explore therapeutic strategies targeting inflammatory pathways and the role of immunometabolism and discuss biomarker discovery and personalized treatment plans. The final section examines the tumor microenvironment, the microbiome's role, and the intersection of immunotherapy and inflammation. The book offers numerous benefits to its audience. For scientists and researchers, it provides cutting-edge knowledge to inspire new research directions and foster interdisciplinary collaboration while serving as a valuable educational tool for the next generation of researchers.
  • On Human Nature

    Biology, Psychology, Ethics, Politics, and Religion
    • 2nd Edition
    • Michel Tibayrenc
    • English
    This second edition of On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human biological and cultural diversity and its adaptative significance through an extensive selection of representative chapters. It brings together specialists from various fields, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. Edited by renowned expert Michel Tibayrenc, this second edition features updates to all major sections of the first edition and brings novel chapters covering critical advancements in human biology, psychology, behavior, ethics, and culture. A globally diverse and interdisciplinary team of experts has been carefully selected to cover the breadth of topics enclosed. The book is at the crossroads between biology and social sciences. On Human Nature is accessible not only to specialists, but also to students, professors, industry professionals, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon.