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Academic Press

  • Biology of Aging Accelerators

    Fundamentals, Hallmarks and Therapeutic Interventions
    • 1st Edition
    • Sandeep Kumar Singh + 1 more
    • English
    Biology of Aging Accelerators: Fundamentals, Hallmarks and Therapeutic Interventions explores how biological, genetic, and environmental factors affect cellular and systemic homeostasis and lead to accelerated aging. The book begins with a historical perspectives, highlighting the growth in immune system deterioration, chronic illness, and social issues. It then examines the hallmarks of aging, including primary, antagonistic, and integrative characteristics that may or may not be contributors. Subsequent chapters explore basic concepts and key accelerators in human biology, the role of biological clocks, and mechanisms of aging accelerators such as cellular senescence, DNA damage, and mitochondrial dysfunction.The book also addresses how different organs age at different rates and the brain's role as the body's aging integrator and provides actionable insights into innovative therapies aimed at reducing or stopping the signs and symptoms of aging, including developments in medications, lifestyle adjustments, regenerative medicine, and cutting-edge technologies like stem cell therapy and CRISPR. By integrating scientific research and practical insights, this book offers a realistic perspective on anti-aging research and stimulates novel ideas for improving quality of life.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Green Intrusion Detection Systems for IoT

    • 1st Edition
    • Saeid Jamshidi + 3 more
    • English
    Green Intrusion Detection Systems for IoT tackles the pressing security challenges posed by the rapid expansion of the Internet of Things (IoT). The book delves into innovative, lightweight security models and energy-aware IDS mechanisms that strike a balance between security efficacy, computational efficiency, and environmental sustainability. Sections discuss the transformative role of IoT and the need for sustainable security solutions, highlight the distinctions between traditional and Green IDS, focus on lightweight security models essential for resource-constrained IoT devices, and delve into energy-efficient network designs.Additional sections explore green IDS mechanisms, including machine learning and distributed approaches, IoT vulnerabilities and mitigation strategies, practical examples of sustainable IDS in various smart environments, real-world case studies, and future directions in sustainable IoT security. The book concludes with actionable recommendations that align technological advancements with global sustainability goals.

  • Marine Mercury Bioaccumulation

    • 1st Edition
    • Luiz Drude de Lacerda
    • English
    Marine Mercury Bioaccumulation presents state-of-the-art research on mercury bioaccumulation in marine life. Written by leading experts in marine toxicology, this book delivers the latest information on monitoring and modeling mercury biomagnification in key marine taxa. Early chapters introduce the basic biology and ecology of how mercury travels through marine organisms and accumulates within marine food webs. Central chapters discuss the current status and exposure risks of key taxa, including marine vegetation, invertebrates, fishes, mammals, and birds. The book concludes with an assessment of human exposure to mercury through seafood products and novel modeling tools to assess environmental exposure risks and bioaccumulation.User... will find this to be a great resource for a global assessment of mercury contamination in the ocean, including biological resources, monitoring and modeling, current tools, existing research gaps, and suggestions on how to improve our monitoring and policy tools for improved safety of marine life and human consumption. This is an indispensable tool for researchers, resource managers, fisheries stakeholders, and students alike.

  • Protein Kinase Inhibitors

    The Promise of Natural Products in Cancer Therapeutics
    • 1st Edition
    • Md. Imtaiyaz Hassan + 1 more
    • English
    Protein Kinase Inhibitors: The Promise of Natural Products in Cancer Therapeutics explores a novel therapeutic avenue for cancer treatment through nutraceutical-based kinase inhibitors. The book covers their historical background, outlook, mechanistic pathways, and clinical aspects, highlighting their relevance in cancer therapy. It also examines the potential of polyphenolic derivatives and other natural compounds in inhibiting key kinases involved in major cancer signaling pathways, focusing on their application in clinical trials and marketed drugs. Sections explore the implications of polyphenols in cancer management, novel sources of breast cancer inhibitors, the role of natural products in lymphoma therapy, and the multitarget potential of phytochemicals. Each chapter is designed to provide a thorough understanding of how natural products can be harnessed to develop innovative cancer therapeutics. It will serve as a valuable resource for academics, scientists, young researchers, students, and pharmacists working or interested in kinase biology and cancer therapeutics with its unique perspective on using nature's own arsenal to combat cancer.

  • Smart Hospital Anatomy with Advanced Sensors

    Innovations in Patient Care
    • 1st Edition
    • Amit Kumar Tyagi + 1 more
    • English
    Smart Hospital Technology with Advanced Sensors: Innovations in Patient Care explores the transformative role of advanced sensor systems in modern healthcare environments. This edited book presents a comprehensive overview of smart hospital technologies, emphasizing the integration of AI, IoT, and automation to enhance patient care and hospital operations. The book covers a wide range of topics including wearable and implantable sensors, AI-driven diagnostics, robotic surgery, smart ICUs, and cybersecurity in healthcare. It also addresses emerging trends such as blockchain for medical data, ethical AI, and the convergence of smart hospitals with smart cities, supported by global case studies and expert contributions. Designed for students, researchers, and academics in bioinformatics, this book offers foundational knowledge, current applications, and future directions in digital healthcare. It serves as a valuable resource for understanding the challenges and opportunities in building intelligent, data-driven hospital systems that improve outcomes and redefine patient experiences.

  • The Fauna of Australia’s Tropical Savanna Biome

    Biodiversity, Biogeography, and Conservation
    • 1st Edition
    • Alan Andersen + 1 more
    • English
    The Fauna of Australia's Tropical Savanna Biome: Biodiversity, Biogeography and Conservation considers the full range of vegetation types and freshwater systems that occur within the dominant savanna matrix in Australia's monsoonal tropics. Edited by renowned experts of tropical ecology, it provides descriptions of diversity, taxonomic, functional composition and endemism, and ecological and biogeographical questions of wide interest. Chapters explore how diversity and composition vary among different habitats in a savanna landscape and along the savanna rainfall gradient. The book also considers how distinctive savanna fauna is within Australia and compared with tropical savannas elsewhere in the world. The book considers the unique biogeographic and evolutionary history of this highly diverse and distinctive biome, building on a rich foundation of knowledge accrued over decades of research on many aspects of the region's biodiversity, conservation values, and challenges. This is an indispensable resource for students and researchers studying tropical biodiversity, as well as conservationists and land managers of Australia's tropical savanna biome and those found across the globe.

  • The Future of Pharma Across All Sectors in the Artificial Intelligence Era

    • 1st Edition
    • Miltiadis Lytras + 5 more
    • English
    The Future of Pharma Across All Sectors in the Artificial Intelligence Era offers a thorough examination of the pharmaceutical industry's current landscape, highlighting the myriad challenges, opportunities, and trends that are poised to shape its future. Edited by experts, this book delves into transformative technological advancements, including artificial intelligence, machine learning, big data analytics, and blockchain. These technologies are redefining pharmaceutical research, development, and commercialization, making precision medicine and personalized therapies a reality, while integrating genomic medicine into the pharmaceutical value chain.Additionally, the book addresses educational implications for academic curricula, emphasizing the need for digital transformation in healthcare delivery models. It scrutinizes regulatory trends and compliance, offering insights into navigating complex landscapes to ensure product quality and safety. The book emphasizes the pharmaceutical industry's role in tackling infectious diseases and health disparities, promoting health equity through innovative drug development and access initiatives. Future trends and predictions are speculated upon, considering demographic shifts and evolving healthcare needs, while market dynamics and commercial strategies are analyzed to equip pharmaceutical companies with practical recommendations for navigating competitive landscapes.

  • A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management

    • 1st Edition
    • Scott G. Pritzlaff + 4 more
    • English
    A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management explores the theoretical foundations, clinical applications, and technical nuances of DRG stimulation, providing a robust framework for understanding and implementing this advanced pain management technique. The book consolidates current best practices, novel technical considerations, and emerging research into a single, authoritative volume. Main themes include the anatomical and physiological basis of DRG stimulation, clinical indications, patient selection, surgical techniques, device programming, and long-term patient outcomes. By integrating insights from leading experts in the field, the book provides a comprehensive and practical guide for clinicians, researchers, and students. Distinct from existing titles that merely touch upon the subject, this book offers a detailed and specialized focus on DRG stimulation, including up-to-date evidence, clinical guidelines, and case studies. The book also features pedagogical elements such as learning objectives, review questions, and case studies to enhance understanding and application.

  • Insights for Researchers and Clinicians to Navigating Kidney Stone Surgery

    A Comparative Narrative of Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Kidney Stones
    • 1st Edition
    • Oktay Ozman + 1 more
    • English
    Insights for Researchers and Clinicians to Navigating Kidney Stone Surgery: A Comparative Narrative of Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Kidney Stones is the ultimate resource for healthcare professionals seeking to excel in the field of kidney stone surgery. The book provides a comparative history of RIRS and PCNL, exploring their evolution from early attempts at endoscopic stone removal to the development of flexible ureteroscopy and technique refinement. It covers instrumentation, including access sheaths, ureteroscopes, energy sources, and fluoroscopy. Patient selection criteria, anesthesia techniques, and intraoperative monitoring are thoroughly examined.The book offers detailed guidance on kidney access, including transureteral and percutaneous approaches, and discusses fragmentation and stone retrieval methods, comparing their efficacy and outcomes. Complications, management strategies, postoperative care, and long-term outcomes assessment are extensively discussed, ensuring a comprehensive understanding of patient care. With its comprehensive coverage and contributions from renowned experts, the book equips healthcare professionals with the knowledge and skills needed to excel in the rapidly evolving field of minimally invasive kidney stone management.

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