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Elsevier

Academic Press

  • The Pharmacological Potential of Cyanobacteria

    • 1st Edition
    • Graciliana Lopes + 2 more
    • English
    The Pharmacological Potential of Cyanobacteria explores the bioactive compounds isolated from cyanobacteria and their relationship to human health and biotechnological applications. The book presents an overview of the chemistry and ecology of cyanobacteria, focusing on culture needs and techniques of biomass production. It is organized according to the different biological activities and biotechnological applications of compounds discovered in recent years. Besides biological activity, the mechanism of action of compounds is explained, along with molecular structure. Finally, compounds already used in therapeutics and biotechnology, as well as those in phases of approval or clinical trials are explored. Each chapter is written by a different research group with expertise in the field and publications in peer reviewed journals. Researchers and students in pharmaceutical academic research, pharmaceutical industrial sector personnel, health professionals, and nutritionists will find this book to be very useful.

  • Diabetes Without Needles

    Non-invasive Diagnostics and Health Management
    • 1st Edition
    • Artur Rydosz
    • English
    Diabetes Without Needles: Non-invasive Diagnostics and Health Management provides a comprehensive and objective compilation of the most promising noninvasive methods for glucose monitoring, including an in-depth analysis of their advantages and disadvantages in terms of biochemical processes. The latest advances in the field are discussed, including methods such as optical measurements, electrochemical measurements, exhaled breath analysis, direct measurements of glucose in the blood using noninvasive techniques, and the indirect analysis of biomarkers that are related to the glycemia. The book's author also presents recommendations for future research directions in this field. This book is a valuable resource for researchers in the areas of diabetes, noninvasive methods and diagnostics development.

  • Innovative Data Integration and Conceptual Space Modeling for COVID, Cancer, and Cardiac Care

    • 1st Edition
    • Amy Neustein + 1 more
    • English
    In recent years, scientific research and translation medicine have placed increased emphasis on computational methodology and data curation across many disciplines, both to advance underlying science and to instantiate precision-medicine protocols in the lab and in clinical practice. The nexus of concerns related to oncology, cardiology, and virology (SARS-CoV-2) presents a fortuitous context within which to examine the theory and practice of biomedical data curation. Innovative Data Integration and Conceptual Space Modeling for COVID, Cancer, and Cardiac Care argues that a well-rounded approach to data modeling should optimally embrace multiple perspectives inasmuch as data-modeling is neither a purely formal nor a purely conceptual discipline, but rather a hybrid of both. On the one hand, data models are designed for use by computer software components, and are, consequently, constrained by the mechanistic demands of software environments; data modeling strategies must accept the formal rigors imposed by unambiguous data-sharing and query-evaluation logic. In particular, data models are not well-suited for software-level deployment if such models do not translate seamlessly to clear strategies for querying data and ensuring data integrity as information is moved across multiple points. On the other hand, data modeling is, likewise, constrained by human conceptual tendencies, because the information which is managed by databases and data networks is ultimately intended to be visualized/utilized by humans as the end-user. Thus, at the intersection of both formal and humanistic methodology, data modeling takes on elements of both logico-mathematical frameworks (e.g., type systems and graph theory) and conceptual/philosoph... paradigms (e.g., linguistics and cognitive science). The authors embrace this two-sided aspect of data models by seeking non-reductionistic points of convergence between formal and humanistic/conceptua... viewpoints, and by leveraging biomedical contexts (viz., COVID, Cancer, and Cardiac Care) so as to provide motivating examples and case-studies in this volume.

  • Autonomous and Connected Heavy Vehicle Technology

    • 1st Edition
    • Rajalakshmi Krishnamurthi + 2 more
    • English
    Autonomous and Connected Heavy Vehicle Technology presents the fundamentals, definitions, technologies, standards and future developments of autonomous and connected heavy vehicles. This book provides insights into various issues pertaining to heavy vehicle technology and helps users develop solutions towards autonomous, connected, cognitive solutions through the convergence of Big Data, IoT, cloud computing and cognition analysis. Various physical, cyber-physical and computational key points related to connected vehicles are covered, along with concepts such as edge computing, dynamic resource optimization, engineering process, methodology and future directions. The book also contains a wide range of case studies that help to identify research problems and an analysis of the issues and synthesis solutions. This essential resource for graduate-level students from different engineering disciplines such as automotive and mechanical engineering, computer science, data science and business analytics combines both basic concepts and advanced level content from technical experts.

  • Current Topics in iPSCs Technology

    • 1st Edition
    • Volume 17
    • Alexander Birbrair
    • English
    Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business.

  • Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies covers the neuronal cell communication system in excitable cells, recognizing the most relevant mechanisms of cell communication. Along with new findings in biotechnology, medicine and pathological cases for clinicians, the book highlights electrochemical potential in living nerve and muscle cells. Written for physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists, this book an essential read for a real understanding of the signals as we see them.

  • Differential Equations with Mathematica

    • 5th Edition
    • Martha L. Abell + 1 more
    • English
    Differential Equations with Mathematica, Fifth Edition uses the fundamental concepts of the popular platform to solve (analytically, numerically, and/or graphically) differential equations of interest to students, instructors, and scientists. Mathematica’s diversity makes it particularly well suited to performing calculations encountered when solving many ordinary and partial differential equations. In some cases, Mathematica’s built-in functions can immediately solve a differential equation by providing an explicit, implicit, or numerical solution. In other cases, Mathematica can be used to perform the calculations encountered when solving a differential equation. Because one goal of elementary differential equations courses is to introduce students to basic methods and algorithms so that they gain proficiency in them, nearly every topic covered this book introduces basic commands, also including typical examples of their application. A study of differential equations relies on concepts from calculus and linear algebra, so this text also includes discussions of relevant commands useful in those areas. In many cases, seeing a solution graphically is most meaningful, so the book relies heavily on Mathematica’s outstanding graphics capabilities.

  • Clinical Ophthalmic Genetics and Genomics

    • 1st Edition
    • Graeme C.M. Black + 2 more
    • English
    Clinical Ophthalmic Genetics and Genomics provides an accessible, clinically-focused reference for the evolving field of Genetic Ophthalmology. This well-organised, easy-to-read textbook integrates key concepts with clinical practice and is designed to enhance effective learning and retention of complex material. It includes contributions from recognised leaders in the field and provides expert guidance on the complete spectrum of genetic ophthalmic disorders.

  • Biomarkers in Bipolar Disorders

    • 1st Edition
    • Rodrigo Machado-Vieira + 1 more
    • English
    Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes... prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder.

  • Chronic Obstructive Pulmonary Disease (COPD) Diagnosis using Electromyography (EMG)

    • 1st Edition
    • Archana Bajirao Kanwade + 1 more
    • English
    Chronic Obstructive Pulmonary Disease (COPD) Diagnosis using Electromyography (EMG) presents a new and innovative method of COPD diagnosis using EMG to analyze sternomastoid muscle activity using features extraction and classification. The book describes the methodology of EMG analysis, the slope-based onset detection algorithm and SEMG analysis in time, frequency and time frequency domain analyses. It also explores the identification of frequencies for single frequency Continuous Wavelet Transform (CWT) analysis and feature extraction and selection for successful classification COPD into its severity grades. The book provides a compilation of all techniques used in the literatures and emphasizes newly proposed techniques for the early detection of COPD. Fully comprehensive, the book includes discussion of limitations of existing methods for COPD diagnosis and introduces new efficient methods for COPD identification, classification and early diagnosis.

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