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  • Intelligent Cyber-Physical Systems for Sustainable Healthcare

    • 1st Edition
    • Vandana Bajaj + 5 more
    • English
    Intelligent Cyber-Physical Systems for Sustainable Healthcare addresses the integration of emerging technologies like Virtual Reality, Smart Robotics, and Human-Computer Interaction, which are crucial for maximizing digital health's potential. The book includes case studies that highlight challenges faced by medical practitioners and industry professionals, providing valuable insights for designing sustainable iCPS solutions. Aimed at biomedical engineers, researchers, and industry professionals, it offers guidance for developing practical applications in sustainable healthcare. Additionally, shared, cross-disciplinary experiences assist engineers with less clinical expertise in enhancing healthcare applications in the intelligent digital health sector. Overall, case studies illustrate past challenges in the healthcare industry and present effective solutions to overcome them, making the book a comprehensive resource for advancing sustainable healthcare practices.

  • Phytotoxicity of Organic Pollutants

    Impacts and Management
    • 1st Edition
    • Golam Jalal Ahammed + 1 more
    • English
    Phytotoxicity of Organic Pollutants: Impacts and Management offers new insights into understanding the mechanisms of plant response to organic pollutants and their impact on plant developmental biology and stress tolerance. The book provides coverage on the phytotoxicity and the deleterious effects of various organic pollutants on the mechanisms of plant growth, development, and responses to stress. It also considers environmental and plant-based remediation strategies to mitigate the impact phytotoxicity of organic pollutants and examines the broader potential implications of their impact on food safety and environmental sustainability. Phytotoxicity of Organic Pollutants is an interdisciplinary resource for scientists, academics, graduate students, and industry professionals interested in the study and remediation of the phytotoxicity of contaminants.

  • Phytochemicals and Hallmarks of Cancer

    From Molecules to Medicine
    • 1st Edition
    • Gautam Sethi + 1 more
    • English
    Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine delves into the potential of phytomedicine to effectively address both established and emerging hallmarks of cancer, offering valuable insights into their translational applications from bench to bedside. The book provides comprehensive information about how the plant-derived product tackles cancer by targeting different hall markers that drive cancer progression. In 12 chapters the book not only describes the implications of plant products on cancer immunotherapy, gives insight in the hurdles in clinical translating plant derived products for cancer therapy, but also focuses on the therapeutic aspects of phytochemicals, providing insights into how understanding of mechanism of actions of phytochemicals can aid to develop innovative therapies.By addressing these knowledge and information needs Phytochemicals and Hallmarks of Cancer: From Molecules to Medicine is designed to be accessible to clinicians and researchers alike in the field of phytochemical applications in medicine.

  • Innovations in Robotic Design, Control, and Rehabilitation Dynamics

    • 1st Edition
    • Ahmad Taher Azar + 1 more
    • English
    Innovations in Robotic Design, Control, and Rehabilitation Dynamics explores a wide range of topics, from biomechanics-inspire... exoskeletons to neural control strategies for mobile robot swarms. From autonomous vehicles to medical robotics, this book delves into the latest advancements in modeling, dynamics, and control. Each chapter offers insights essential for navigating the complexities of modern robotic systems. By focusing on precise modeling techniques, researchers aim to better understand and predict robot behavior while advanced control strategies optimize performance and adaptability in dynamic environments. With a keen eye on integrating sensory feedback and perception systems, robots are becoming increasingly autonomous and intelligent. Whether you're interested in cable-driven haptic devices or AI-enhanced biosensors in medical robotics, this book provides a deep-dive into cutting-edge developments shaping the future of robotics.

  • Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer

    • 1st Edition
    • Volume 207
    • English
    Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer, Volume 207 covers the latest techniques and strategies used to investigate and boost cytotoxic activity in cells targeting cancer. Chapters include An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol, New protocol to measure mitochondria polarization/functio... at the immunological synapse, Analysis of CAR-T cell–mediated cytotoxicity in solid tumor models, Investigation of the in vitro lytic capacity of CAR-T by microscopyal, Antigen-specific T cell cytotoxicity toward target tumor cells, In vitro expansion of stem-like memory T cells via D-mannose supplementation, and much more.Additional chapters explore High-throughput time-lapse imaging of B16 target cell killing by ovalbumin-specific CD8+ T cells, Evaluation of an intracellular magneto-mechanical approach for regulating dendritic cell activation, Analyzing the effect of NK cells on in-vivo models of tumor dissemination by digital pathology and flow cytometry, Super-resolution imaging of the NK cell synapse on supported lipid bilayers using MINFLUX nanoscopy, ASSESSMENT OF NK CELL CYTOTOXICITY INDUCED BY IL-15 BASED IMMUNOTHERAPY AGAINST CANCER CELLS, Combined phenotyping and functional analysis of isolated human natural killer cells using spectral flow cytometry, and much more.

  • Advances in Biosystems

    • 1st Edition
    • Xiaoli Li + 2 more
    • English
    Advances in Biosystems investigates the latest techniques for evaluating, detecting, measuring, and enhancing the functional bioactivities, chemical composition, and physicochemical characteristics of animal, plant, and environmental biosystems. This comprehensive, interdisciplinary handbook provides detailed explanations for tracking functional molecules during various biological processes, along with practical methodologies for both laboratory and industrial applications. Sections cover cellular biosystems advances, including single-cell microsystems and tissue system biology of plants and animals, alongside biomass microsystems and agricultural biosystems advances, exploring innovations in animal, plant, and crop biosystems, as well as food hydrocolloids and biotechnological advancements.Additio... content addresses environmental biosystems, discussing colloidal biosystems, nano and micro-biosystems, chemical toxicology, eco-friendly biosystems, and green chemistry, pharmaceutical biosystems, highlighting medical biosystems, human cellular metabolomics, nutrigenomics, and precision medicine applications. A final section presents in-depth analytical methods for tracking these various biosystems, including high-throughput technologies, deep learning, machine learning, bioinformatics models, and spectroscopic and sensor-based techniques.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 149
    • English
    Advances in Heterocyclic Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Gene Therapy in Neurodegenerative Disorders

    From Bench to Bedside
    • 1st Edition
    • Vahid Mansouri + 1 more
    • English
    Gene Therapy in Neurodegenerative Disorders: From Bench to Bedside offers a comprehensive review of gene therapy modalities and their applications in treating neurodegenerative disorders. Initial chapters focus on the fundamentals of gene therapy strategies, including gene delivery methods and CNS-targeted gene delivery. Subsequent chapters delve into specific neurodegenerative disorders such as Spinal Muscular Atrophy (SMA), Amyotrophic Lateral Sclerosis (ALS), Duchenne Muscular Dystrophy (DMD), and Alzheimer's Disease (AD), highlighting the latest gene therapy approaches for each condition. Each chapter provides a detailed introduction to the relevant field before exploring specific tools and applications.With contributions from leading experts, the book addresses current and ongoing clinical trials, potential challenges, and promising advances in gene therapy for neurodegenerative disorders. It also discusses regulatory and ethical considerations in translating research from bench to bedside. This book is an essential resource for basic science researchers in gene therapy, geneticists, biotechnologists, and clinical researchers seeking new and effective treatments for neurodegenerative diseases. It equips readers with the knowledge and tools needed to advance their work and drive innovation in gene therapy.

  • Biomechanics and Mechanobiology of Bone

    From Model to Patient
    • 1st Edition
    • Luis Cardoso + 2 more
    • English
    Biomechanics and Mechanobiology of Bone: From Model to Patient provides readers with a comprehensive overview of the modelling and assessment of bone biomechanics. It addresses topics such as biosubstitutes and bone implants from the point of view of design, properties, computational modeling, and choice of biomaterials. It concentrates on the biomechanics and mechanobiology modeling approaches of bone, including biological models, multiphysical approaches, surface and volumetric growth models, and bone fluid flow models. This is augmented by case studies and examples of models for computer-aided diagnosis, treatment, and monitoring of bone diseases. Readers are introduced to bone physiology, adaptation, and disease, including cellular aspects at the root of bone mechanotransduction and leading to bone growth and remodeling, and management of diseases. Chapters also cover the mechanical, multiphysical multiscale properties of bone and constitutive laws including bone viscoelasticity, poroelasticity, bone damage, fatigue and fracture, as well as measurement techniques of bone properties.

  • Multifunctional Nano pharmaceuticals for Biomedical Applications

    • 1st Edition
    • Sushil K. Kashaw + 3 more
    • English
    Multifunctional Nanopharmaceuticals for Biomedical Applications covers the latest advancements in multifunctional nanopharmaceuticals while also addressing the pressing need for innovative solutions for unmet medical challenges. Each chapter explores key topics such as the fundamentals of nanotechnology and drug delivery, PEGylated lipid carriers for cancer theranostics, and the latest in biomimetic nanomicells and nanorobots. With detailed discussions on design strategies, formulation techniques, and regulatory aspects, readers will gain a thorough understanding of the complexities and innovations in this dynamic field. The exploration of clinical applications and future trends also equips readers with the knowledge to navigate the evolving landscape of nanomedicine.This is an essential resource for researchers interested in the transformative potential of nanotechnology in drug delivery and disease treatment. It empowers readers to harness cutting-edge technologies for effective therapies, paving the way for a new era of personalized, precise, and potent medicine. With the rapid evolution of nanomedicine, this book serves as a crucial tool for researchers, students, healthcare professionals, and industry experts alike, bridging the gap between fundamental concepts and their real-world applications.

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