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Academic Press

  • Clinical Immunobiology

    • 1st Edition
    • Volume 2
    • Fritz H. Bach + 1 more
    • English
    Clinical Immunobiology, Volume 2 covers the advances in the field being made to apply bone marrow transplantation to the treatment of several diseases. This volume is divided into 11 chapters and begins with surveys of the clinical considerations of bone marrow transplantation. Considerable chapters are devoted to the application of this transplantation to the treatment of various diseases, including aplastic anemia, aregenerative pancytopenia, leukemia, uniformly fatal severe combined immunodeficiency diseases, and Wiskott-Aldrich syndrome. Other chapters examine the cellular engineering in the form of bone marrow and thymus transplantation. The remaining chapters consider the effects of exposure to excessive amounts of radiation or cytotoxic chemicals, as well as the hematopoietic failure based on malfunction of the complex process of normal hematological development and maintenance. This book will be of great value to clinical immunobiologists, practicing physicians, researchers, and medical and biology students.
  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 3
    • Norman J. Lass
    • English
    Speech and Language: Volume 3, Advances in Basic Research and Practice is a compendium of papers that discusses theories, clinical issues, and pathology of language and speech. Some papers discuss theories of phonological development, the encoding/decoding system of language, and the application of phonological universals in speech pathology. Other papers deal with the role of the speech-language clinician, a psychological framework for speech perception, and the formulation of a model for biomechanical analysis of velopharyngeal structure and function. Several papers analyze speech control mechanisms in skilled and non-skilled speakers, the rationale for the delayed auditory feedback (DAF) treatment program, and biofeedback in relation to speech pathology. One paper cites a study of Williams (1974) that shows strategies used in learning a new phonetic system depend upon whether the speaker is still within the critical period for language learning or already well beyond it. The paper notes that if adults can ignore their previously learned sound system and be childlike again in their freedom to experiment and be sensitivity to their own results, then they can achieve supra-segmental and segmental nuances of a new language. The compendium can prove helpful for linguists, ethnologists, psychologists, speech therapists, researchers in linguistics or communications, and general readers interested in speech or learning issues.
  • The Role of Products of the Histocompatibility Gene Complex in Immune Responses

    • 1st Edition
    • David H. Katz + 1 more
    • English
    The Role of Products of the Histocompatibility Gene Complex in Immune Responses documents the proceedings of a conference held on 3-7 November 1975, which brought together an international group of scientists spanning three independent disciplines—genetics and immunogenetics, molecular biochemistry, and immunobiology—with clinical medicine overlapping these disciplines. This volume contains 42 papers organized according to the eight sessions held at the conference. The papers in Session I examined the genetics of the major histocompatibility complex. Session II presented studies on the biology of mixed lymphocyte interactions and cell-mediated cytotoxicity reactions. Session III discussed immune response gene systems while Session IV dealt with the genetic control of cell interactions. The papers in Session V covered idiotypic determinants on T cell receptors. Session VI investigated the properties of histocompatibility gene products involved in regulation of immune responses. Session VII focused on the biochemistry and immunocytology of cell surface products of the major histocompatibility complex. Finally, Session VIII discussed interrelationships between products of the major histocompatibility complex and their relevance to disease.
  • Biochemistry LabFax

    • 1st Edition
    • English
    LABFAX volumes are purpose-designed data reference books for practising scientists. Each book presents key information for a major subject in one place and so saves hours of searching. It does not simply collect together data which are already available in catalogues since these are often incomplete and can contain conflicting information. Rather, the authors and editors of each LABFAX volume have searched the original literature for the accurate data which they know the specialist needs.Biochemistry LabFax is a detailed compendium of essential information - on radioisotopes, enzymes, proteins, nucleic acids, lipids, plus data on selected techniques such as chromatography, electrophoresis, etc. - needed on an almost daily basis by researchers in any area of biochemistry. In addition, the book acts as a gateway to other sources for information more specific than can be covered in a volume of this size.
  • Transfer Factor

    Basic Properties and Clinical Applications
    • 1st Edition
    • Michael S. Ascher + 2 more
    • English
    Transfer Factor: Basic Properties and Clinical Applications covers papers about transfer factor. The book presents papers on the in vitro studies of transfer factor; the characterization of transfer factor; and the animal models of transfer factor. The text also includes articles on the use of transfer factor in infectious and neoplastic diseases and transfer factor therapy. Examples of papers on transfer factor therapy include the role of transfer factor in the treatment of lymphoma cutis in Wiskott-Aldrich syndrome, transfer factor immunotherapy of rheumatoid arthritis, and transfer factor therapy in a patient with an isolated T-cell deficiency. Immunologists, pathologists, oncologists, microbiologists and people involved in the study of infectious diseases will find the book invaluable.
  • Natural and Induced Cell-Mediated Cytotoxicity

    Effector and Regulatory Mechanisms
    • 1st Edition
    • Gert Riethmüller + 2 more
    • English
    Natural and Induced Cell-Mediated Cytotoxicity: Effector and Regulatory Mechanisms contains the proceedings of the Erwin Riesch Symposium organized on the occasion of the Fifth Centennial of the University of Tübingen in Germany on October 20-23, 1977. The symposium provided a forum for reviewing the progress that has been made in understanding the effector and regulatory mechanisms underlying natural and induced cell-mediated cytotoxicity. Topics covered range from the immunobiology of natural killer cells to the role of macrophages as regulator, accessory, and effector cells in cytotoxicity. Comprised of 27 chapters, this book begins by analyzing the characteristics of natural cytotoxic cells in mice, followed by a discussion on the generation in vivo of mouse natural cytotoxic cells and the role of cytotoxic T cells in the local defense against solid tumors. Subsequent chapters focus on the natural cytotoxicity of human lymphocytes; opposing effects of interferon on natural killer and target cells; susceptibility of cloned melanoma to natural cytotoxicity; and cell-mediated immunity against avian virus-induced tumor cells. The book also examines alternative routes of entry for cell surface antigens into the immune system before concluding with a chapter that considers interferon induction by Corynebacterium parvum. This monograph should be of value to students, researchers, and practitioners in the fields of biology and immunology.
  • Linear Panel Analysis

    Models of Quantitative Change
    • 1st Edition
    • Ronald C. Kessler
    • English
    Linear Panel Analysis: Models of Quantitative Change focuses on the use of linear models in the analysis of change data measured on a sample of individuals over multiple time points. This book is organized into 12 chapters. After a general introduction to change analysis in Chapter 1, some basic algebraic results on change scores are presented in Chapter 2. Chapter 3 constructs and analyzes structural equation models for studying the causes of change, while Chapter 4 outlines several ways of simply describing change in groups. The uses and abuses of cross-lagged panel correlations are discussed in Chapter 5. Chapters 6 to 10 deal with a variety of special topics that arise in panel analysis. The alternatives to the analysis of over-time data for a set of individuals are described in Chapter 11. The last chapter is devoted to the practical aspects of designing and carrying out the data collection phase of a panel study. This publication is intended for social scientists who work with change data.
  • Immunobiology of the Complement System

    An Introduction for Research and Clinical Medicine
    • 1st Edition
    • Gordon D. Ross
    • English
    Immunobiology of the Complement System: An Introduction for Research and Clinical Medicine provides an introduction to the complement system. The intention was to create a primer that would provide the basic knowledge of complement required for either research or clinical medicine in diseases involving the complement system. The book begins with a historical background of complement research; it introduces certain key investigators from the past who have made important contributions. Separate chapters on the basic aspects of complement function are followed by chapters on the molecular genetics of complement and the role of complement in different diseases. Key topics discussed include the activation of complement via the classical pathway and the alternative pathway; complement mediators of inflammation; opsonization and membrane complement receptors; assembly and functions of the terminal components; and complement-dependent mechanisms of virus neutralization. This book has been written primarily for students and scientists who have not been specifically trained in complement research.
  • Handbook of Perception: Perceptual Processing v. 9

    • 1st Edition
    • SWAINE
    • English
    Handbook of Perception, Volume IX: Perceptual Processing covers perceptual processing mechanisms, such as attention, search, selection, pattern recognition, and perceptual learning. This volume contains articles that tackle topics on the mechanisms of attention, perceptual structure and selection, selection and categorization in visual search, and the psychological processes in pattern recognition. Subjects on how individual letters are processed, eye movements, perceptual learning, possible explanations of stimulus ambiguity, and perceptual anomalies, distortions, and disorders. This book will be of use to psychologists, biologists, and those interested in the study of perceptual processing.
  • Current Topics in Cellular Regulation

    • 1st Edition
    • Volume 6
    • Bernard L. Horecker + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 6 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation. Organized into eight chapters, this volume begins with an overview of the well-defined stages of sporulation that can be correlated with the appearance of several enzymes, ultrastructures, and chemical components associated with the developing spore. This text then examines the regulatory properties of G6PD from various sources, with emphasis to those cells in which these properties may operate in vivo in the control of carbohydrate metabolism. Other chapters consider the various methods for analyzing biochemical systems. The final chapter deals with kinetic cooperativity, which is the basis of the flip-flop mechanism. This book is a valuable resource for biochemists, biologists, and research workers.